Genomic DNA methylation: the mark and its mediators

RJ Klose, AP Bird - Trends in biochemical sciences, 2006 - cell.com
… by which DNA methylation is targeted to specific regions of the genome and interpreted by
methyl-CpG-binding proteins. Recent studies have illuminated the role of DNA methylation in …

DNA methylation: a profile of methods and applications

MF Fraga, M Esteller - Biotechniques, 2018 - Taylor & Francis
… Ever since methylcytosine was found in genomic DNA, this … and qualitative information on
genomic DNA methylation. The … the study of the methylation status of specific DNA sequences. …

Physical activity and global genomic DNA methylation in a cancer-free population

FF Zhang, R Cardarelli, J Carroll, S Zhang, KG Fulda… - Epigenetics, 2011 - Taylor & Francis
… expression through DNA methylation. To assess whether DNA methylation is associated …
, we measured global genomic DNA methylation using bisulfite converted DNA and real time …

Principles and challenges of genome-wide DNA methylation analysis

PW Laird - Nature Reviews Genetics, 2010 - nature.com
… Targeted capture requires relatively large quantities of native genomic DNA or amplification
before hybridization, which would erase DNA methylation information in native genomic DNA

Genome‐wide DNA methylation profiling

M Bibikova, JB Fan - Wiley Interdisciplinary Reviews: Systems …, 2010 - Wiley Online Library
… sequencing technologies, genome-wide bisulfite … -genome approaches have been used
to get the most comprehensive DNA methylation profiles in organisms of various genome sizes. …

LUMA (LUminometric Methylation Assay)—a high throughput method to the analysis of genomic DNA methylation

M Karimi, S Johansson, D Stach, M Corcoran… - Experimental cell …, 2006 - Elsevier
… Here, we report a novel assay for genomic DNA methylation based on DNA cleavage by
restriction endonucleases followed by a polymerase extension assay using the Pyrosequencing…

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

V Bollati, J Schwartz, R Wright, A Litonjua… - Mechanisms of ageing …, 2009 - Elsevier
… , average LINE-1 methylation did not vary over time [p = 0.51]. Our results demonstrate a
progressive loss of DNA methylation in repetitive elements dispersed throughout the genome. …

Significant differences in global genomic DNA methylation by gender and race/ethnicity in peripheral blood

FF Zhang, R Cardarelli, J Carroll, KG Fulda, M Kaur… - Epigenetics, 2011 - Taylor & Francis
… levels of global leukocyte DNA methylation in 161 cancer-… genomic DNA methylation using
bisulfite conversion of DNA … associated with global genomic DNA methylation after controlling …

Whole-genome DNA methylation profiling using MethylCap-seq

AB Brinkman, F Simmer, K Ma, A Kaan, J Zhu… - Methods, 2010 - Elsevier
methylated [1], [2]. This widespread nature poses a challenge for whole-genome profiling of
the DNA methylation … to reveal whole-genome DNA methylation landscapes in human cells …

[HTML][HTML] Plant genomic DNA methylation in response to stresses: Potential applications and challenges in plant breeding

H Peng, J Zhang - Progress in Natural Science, 2009 - Elsevier
… This suggests that methylated alleles are of … genomic DNA methylation under different types
of stress and analyze the possibilities for, and difficulties with, the exploitation of methylated