Vector control: agents of selection on malaria parasites?

CE Oke, VA Ingham, CA Walling, SE Reece - Trends in Parasitology, 2022 - cell.com
Insect vectors are responsible for spreading many infectious diseases, yet interactions
between pathogens/parasites and insect vectors remain poorly understood. Filling this …

Efficacy and safety of moxidectin and albendazole compared with ivermectin and albendazole coadministration in adolescents infected with Trichuris trichiura in …

S Welsche, EC Mrimi, J Hattendorf… - The Lancet infectious …, 2023 - thelancet.com
Background Control efforts against soil-transmitted helminths focus on preventive
chemotherapy with albendazole and mebendazole, however these drugs yield …

Pharmacokinetics of ivermectin metabolites and their activity against Anopheles stephensi mosquitoes

C Kern, P Müller, C Chaccour, ME Liechti, F Hammann… - Malaria journal, 2023 - Springer
Abstract Background Ivermectin (22, 23-dihydroavermectin B1a: H2B1a) is an endectocide
used to treat worm infections and ectoparasites including lice and scabies mites …

Activity of ivermectin and its metabolites against asexual blood stage Plasmodium falciparum and its interactions with antimalarial drugs

A Yipsirimetee, P Tipthara… - Antimicrobial agents …, 2023 - Am Soc Microbiol
Ivermectin is an endectocide used widely to treat a variety of internal and external parasites.
Field trials of ivermectin mass drug administration for malaria transmission control have …

Efficacy and safety of ivermectin for the treatment of Plasmodium falciparum infections in asymptomatic male and female Gabonese adults–a pilot randomized, double …

DE Mbassi, G Mombo-Ngoma, J Held, DG Okwu… - …, 2023 - thelancet.com
Background Ivermectin's mosquitocidal effect and in vitro activity against Plasmodium
falciparum asexual stages are known. Its in vivo blood-schizonticidal efficacy is unknown …

Eliminating malaria vectors with precision-guided sterile males

RA Apte, AL Smidler, JJ Pai, ML Chow, S Chen… - Proceedings of the …, 2024 - pnas.org
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However, existing vector control …

[HTML][HTML] Ivermectin as a novel malaria control tool: Getting ahead of the resistance curse

AB Sagna, L Zéla, COW Ouedraogo, SH Pooda… - Acta Tropica, 2023 - Elsevier
Reduction in malaria clinical cases is strongly dependent on the ability to prevent Anopheles
infectious bites. Vector control strategies using long-lasting insecticidal nets and indoor …

Ivermectin therapy for young children with scabies infection: a multicentre phase 2 non-randomized trial

A Gwee, A Steer, K Phongluxa… - The Lancet Regional …, 2024 - thelancet.com
Background Ivermectin, an effective treatment for scabies, is not licensed for children
weighing< 15 kg. Pharmacokinetic modelling has shown a 3 mg dose in young children (2 …

Entomological impact of mass administration of ivermectin and dihydroartemisinin-piperaquine in The Gambia: a cluster-randomized controlled trial

HM Soumare, ED Dabira, MM Camara, L Jadama… - Parasites & vectors, 2022 - Springer
Background Vector control interventions in sub-Saharan Africa rely on insecticide-treated
nets and indoor residual spraying. Insecticide resistance, poor coverage of interventions …

[HTML][HTML] Eliminating malaria vectors with precision guided sterile males

AL Smidler, RA Apte, JJ Pai, ML Chow, S Chen… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Controlling the principal African malaria vector, the mosquito Anopheles gambiae, is
considered essential to curtail malaria transmission. However existing vector control …