The complex process of oral drug absorption is influenced by a host of drug and formulation
properties as well as their interaction with the gastrointestinal environment in terms of drug …

While each route of therapeutic drug delivery has its own advantages and limitations, oral
delivery is often favored because it offers convenient painless administration, sustained …

Background: Cardiac rhabdomyomas (CRs) are the earliest sign of tuberous sclerosis
complex (TSC). Most of them spontaneously regress after birth. However, multiple and/or …

Among various drug administration routes, oral drug delivery is preferred and is considered
patient-friendly; hence, most of the marketed drugs are available as conventional tablets or …

Previously this laboratory characterized Slc39a8-encoded ZIP8 as a Zn2+/(HCO3–) 2
symporter; yet, the overall physiological importance of ZIP8 at the whole-organism level …

Introduction: A large proportion of prescribed drugs to children are administered orally. Age-
related change in factors affecting oral absorption can have consequences for drug dosing …

Methimazole and propylthiouracil have been used in the management of hyperthyroidism for
more than half a century. However, hepatotoxicity is one of the most deleterious side effects …

Moxifloxacin serum concentrations in children receiving multidrug-resistant tuberculosis
treatment following an oral dose of 10 mg/kg were low. Human immunodeficiency virus …

Introduction: It has been known for a long time that the efficiency and toxicity of drugs
change during a 24-h period. However, the molecular mechanisms involved in these …

Neonatal Infections are among the most common reasons for admission to the intensive
care unit. Neonatal sepsis (NS) significantly contributes to mortality rates. Empiric antibiotic …