DNA methylation is an essential epigenetic modification for mammalian development and is
crucial for the establishment and maintenance of cellular identity. Traditionally, DNA …

Initiation and progression of human caner not only depends on genetic alterations but also
on epigenetic changes such as DNA methylation and histone modifications. Aberrant DNA …

Diffuse large B-cell lymphoma (DLBCL) is the most common aggressive form of non-
Hodgkin lymphoma with variable biology and clinical behavior. The current classification …

Epigenetics has emerged as a new and promising field in recent years. Lifestyle, stress,
drugs, physiopathological situations and pharmacological interventions have a great impact …

Cachexia is a multifactorial syndrome characterized by skeletal muscle loss, with or without
adipose atrophy, irreversible through nutritional support, in the context of systemic …

Background Aberrant hypermethylation of cellular genes is a common phenomenon to
inactivate genes and promote tumorigenesis in nasopharyngeal carcinoma (NPC). Methods …

Carcinogenesis, a complex multifactorial process of the transformation of normal cells into
malignant cells, is characterized by many biologically significant and interdependent …

The epigenomic era has revealed a well-connected network of molecular processes that
shape the chromatin landscape. These processes comprise abnormal methylomes …

Over the last few years the increasing usage of “-omic” platforms, supported by next-
generation sequencing, in the analysis of breast cancer samples has tremendously …

В представленном обзоре систематизированы литературные данные об
используемых в настоящее время инструментальных, цитологических и молекулярных …