[HTML][HTML] The relationship of DNA methylation with age, gender and genotype in twins and healthy controls
Cytosine-5 methylation within CpG dinucleotides is a potentially important mechanism of
epigenetic influence on human traits and disease. In addition to influences of age and …
epigenetic influence on human traits and disease. In addition to influences of age and …
[HTML][HTML] The dynamics of DNA methylation in schizophrenia and related psychiatric disorders
DR Grayson, A Guidotti - Neuropsychopharmacology, 2013 - nature.com
Major psychiatric disorders such as schizophrenia (SZ) and bipolar disorder (BP) with
psychosis (BP+) express a complex symptomatology characterized by positive symptoms …
psychosis (BP+) express a complex symptomatology characterized by positive symptoms …
Epigenetic control
GP Delcuve, M Rastegar… - Journal of cellular …, 2009 - Wiley Online Library
Epigenetics refers to mitotically and/or meiotically heritable variations in gene expression
that are not caused by changes in DNA sequence. Epigenetic mechanisms regulate all …
that are not caused by changes in DNA sequence. Epigenetic mechanisms regulate all …
[HTML][HTML] Epigenetic regulation of genomic stability by vitamin C
JP Brabson, T Leesang, S Mohammad… - Frontiers in genetics, 2021 - frontiersin.org
DNA methylation plays an important role in the maintenance of genomic stability. Ten-
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …
eleven translocation proteins (TETs) are a family of iron (Fe2+) and α-KG-dependent …
[HTML][HTML] The colorful history of active DNA demethylation
Patterns of DNA cytosine methylation are subject to mitotic inheritance in both plants and
vertebrates. Plants use 5-methylcytosine glycosylases and the base excision repair pathway …
vertebrates. Plants use 5-methylcytosine glycosylases and the base excision repair pathway …
DNA methylation alterations exhibit intraindividual stability and interindividual heterogeneity in prostate cancer metastases
MJ Aryee, W Liu, JC Engelmann, P Nuhn… - Science translational …, 2013 - science.org
Human cancers almost ubiquitously harbor epigenetic alterations. Although such alterations
in epigenetic marks, including DNA methylation, are potentially heritable, they can also be …
in epigenetic marks, including DNA methylation, are potentially heritable, they can also be …
Distinct epigenomic features in end-stage failing human hearts
Background—The epigenome refers to marks on the genome, including DNA methylation
and histone modifications, that regulate the expression of underlying genes. A consistent …
and histone modifications, that regulate the expression of underlying genes. A consistent …
[HTML][HTML] NCoR1 is a conserved physiological modulator of muscle mass and oxidative function
H Yamamoto, EG Williams, L Mouchiroud, C Cantó… - Cell, 2011 - cell.com
Transcriptional coregulators control the activity of many transcription factors and are thought
to have wide-ranging effects on gene expression patterns. We show here that muscle …
to have wide-ranging effects on gene expression patterns. We show here that muscle …
Epigenetics, DNA methylation, and chromatin modifying drugs
M Szyf - Annual review of pharmacology and toxicology, 2009 - annualreviews.org
Evidence is emerging that several diseases and behavioral pathologies result from defects
in gene function. The best-studied example is cancer, but other diseases such as …
in gene function. The best-studied example is cancer, but other diseases such as …