DNA methylation is a type of epigenetic marking that strongly influences chromatin structure
and gene expression in plants and mammals. Over the past decade, DNA methylation has …

Epigenetic reprogramming involves processes that lead to the erasure of epigenetic
information, reverting the chromatin template to a less differentiated state. Extensive …

Post-translational modification of chromatin is emerging as an increasingly important
regulator of chromosomal processes. In particular, histone lysine and arginine methylation …

Cytosine methylation is an epigenetically propagated DNA modification that can modify how
the DNA molecule is recognized and expressed. DNA methylation undergoes extensive …

Transcription factors (TFs) bind specifically to discrete regions of mammalian genomes
called cis-regulatory elements. Among those are enhancers, which play key roles in …

The field of epigenetics provides neurobiologists with candidate mechanisms for experience-
dependent changes in gene transcription. The ability to realize the potential of epigenetics in …

Methylation of cytosines and adenines in DNA is a widespread epigenetic mark in both
prokaryotes and eukaryotes. In eukaryotes, it has a profound influence on chromatin …

Active DNA demethylation underlies key facets of reproduction in flowering plants and
mammals and serves a general genome housekeeping function in plants. A family of 5 …

DNA methylation is a major epigenetic modification that is strongly involved in the
physiological control of genome expression. DNA methylation patterns are largely modified …

Cancer is a disease arising from both genetic and epigenetic modifications of DNA that
contribute to changes in gene expression in the cell. Genetic modifications include loss or …