Pathogenesis and management of abdominal aortic aneurysm

J Golledge, S Thanigaimani, JT Powell… - European Heart …, 2023 - academic.oup.com
Abdominal aortic aneurysm (AAA) causes∼ 170 000 deaths annually worldwide. Most
guidelines recommend asymptomatic small AAAs (30 to< 50 mm in women; 30 to< 55 mm in …

Pharmacological therapy of abdominal aortic aneurysm: an update

Y Wang, Z Liu, J Ren, M Xiang - Current vascular …, 2018 - ingentaconnect.com
Background: Abdominal aortic aneurysm (AAA), a progressive segmental abdominal aortic
dilation, is associated with high mortality. AAA is characterized by inflammation, smooth …

Distinct Mechanisms of β-Arrestin–Biased Agonist and Blocker of AT1R in Preventing Aortic Aneurysm and Associated Mortality

ZP Jara, TJ Harford, KD Singh, R Desnoyer… - …, 2023 - Am Heart Assoc
Background: Aortic aneurysm (AA) is a “silent killer” human disease with no effective
treatment. Although the therapeutic potential of various pharmacological agents have been …

Research advances in drug therapy for abdominal aortic aneurysms over the past five years: An updated narrative review

R Li, Y Liu, J Jiang - International Journal of Cardiology, 2023 - Elsevier
Background Abdominal aortic aneurysms (AAA) rupture can lead to patient death. Surgical
treatment is currently the optimal treatment for AAA with large diameter (≥ 50 mm). For AAA …

[HTML][HTML] Exploring drug re-purposing for treatment of abdominal aortic aneurysms: a systematic review and meta-analysis

JSS Kristensen, L Krasniqi, LM Obel… - European Journal of …, 2023 - Elsevier
Objective Large abdominal aortic aneurysms (AAAs) present a significant mortality risk.
While numerous medical interventions have been proposed, no drugs have convincingly …

[HTML][HTML] Renin-angiotensin system blockade does not attenuate abdominal aortic aneurysm growth, rupture rate, or perioperative mortality after elective repair

K Salata, M Syed, MA Hussain, R Eikelboom… - Journal of vascular …, 2018 - Elsevier
Objective The objective of this study was to summarize the literature regarding the effects of
renin-angiotensin system blockade (RASB) using angiotensin-converting enzyme inhibitors …

Renin‐Angiotensin‐Aldosterone System Inhibitors Are Associated With Favorable Outcomes Compared to Beta Blockers in Reducing Mortality Following Abdominal …

N Elsayed, AC Gaffey, A Abou‐Zamzam… - Journal of the …, 2023 - Am Heart Assoc
Background The best medical therapy to control hypertension following abdominal aortic
aneurysm repair is yet to be determined. We therefore examined whether treatment with …

Systematic Review Examining the Association of Angiotensin Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Prescription with Abdominal Aortic …

K Tian, S Thanigaimani, K Gibson… - European Journal of …, 2024 - Elsevier
Objective Whether angiotensin II blockade is an effective medical treatment for abdominal
aortic aneurysms (AAAs) has not been established. This systematic review and meta …

Immunological therapeutics in acute aortic syndrome

LJ Rimmer, S Moughal… - Asian Cardiovascular and …, 2020 - journals.sagepub.com
Acute aortic syndrome is a group of interlinked conditions with common presenting
symptoms, including aortic dissection, penetrating atherosclerotic ulcer, and intramural …

Tratamiento farmacológico de aneurismas de la aorta abdominal

IGC Silerio - Expresiones Médicas, 2021 - erevistas.uacj.mx
El aneurisma aórtico abdominal (AAA) es una dilatación progresiva localizada en la aorta
abdominal, que se asocia a una elevada tasa de mortalidad. Su fisiopatología es compleja …