Epigenetic alterations in the gastrointestinal tract: current and emerging use for biomarkers of cancer
WM Grady - Advances in cancer research, 2021 - Elsevier
Colorectal cancer is a leading cause of cancer related deaths worldwide. One of the
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
hallmarks of cancer and a fundamental trait of virtually all gastrointestinal cancers is …
Long noncoding RNAs: Novel insights into hepatocelluar carcinoma
Recent advances in non-protein coding part of human genome analysis have discovered
extensive transcription of large RNA transcripts that lack of coding protein function, termed …
extensive transcription of large RNA transcripts that lack of coding protein function, termed …
[PDF][PDF] DNA methylation‐based prognosis and epidrivers in hepatocellular carcinoma
A Villanueva, A Portela, S Sayols, C Battiston… - …, 2015 - Wiley Online Library
Epigenetic deregulation has emerged as a driver in human malignancies. There is no clear
understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the …
understanding of the epigenetic alterations in hepatocellular carcinoma (HCC) and of the …
Common DNA methylation alterations in multiple brain regions in autism
Autism spectrum disorders (ASD) are increasingly common neurodevelopmental disorders
defined clinically by a triad of features including impairment in social interaction, impairment …
defined clinically by a triad of features including impairment in social interaction, impairment …
[HTML][HTML] Epigenetics in hepatocellular carcinoma development and therapy: The tip of the iceberg
MG Fernández-Barrena, M Arechederra, L Colyn… - Jhep Reports, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is a deadly tumour whose causative agents are generally
well known, but whose pathogenesis remains poorly understood. Nevertheless, key genetic …
well known, but whose pathogenesis remains poorly understood. Nevertheless, key genetic …
Exploration of liver cancer genomes
T Shibata, H Aburatani - Nature reviews Gastroenterology & hepatology, 2014 - nature.com
Liver cancer is the third leading cause of cancer-related death worldwide. Advances in
sequencing technologies have enabled the examination of liver cancer genomes at high …
sequencing technologies have enabled the examination of liver cancer genomes at high …
Epigenetics of hepatocellular carcinoma
In recent years, large scale genomics and genome-wide studies using comprehensive
genomic tools have reshaped our understanding of cancer evolution and heterogeneity …
genomic tools have reshaped our understanding of cancer evolution and heterogeneity …
Analysis of Ugandan cervical carcinomas identifies human papillomavirus clade–specific epigenome and transcriptome landscapes
Cervical cancer is the most common cancer affecting sub-Saharan African women and is
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
prevalent among HIV-positive (HIV+) individuals. No comprehensive profiling of cancer …
Integrative analysis of DNA methylation and gene expression reveals hepatocellular carcinoma-specific diagnostic biomarkers
J Cheng, D Wei, Y Ji, L Chen, L Yang, G Li, L Wu… - Genome medicine, 2018 - Springer
Background Hepatocellular carcinoma (HCC) is the one of the most common cancers and
lethal diseases in the world. DNA methylation alteration is frequently observed in HCC and …
lethal diseases in the world. DNA methylation alteration is frequently observed in HCC and …
Integrative analysis of genomic and epigenomic regulation of the transcriptome in liver cancer
Hepatocellular carcinoma harbors numerous genomic and epigenomic aberrations of DNA
copy numbers and DNA methylation. Transcriptomic deregulation by these aberrations plays …
copy numbers and DNA methylation. Transcriptomic deregulation by these aberrations plays …