Quantitative susceptibility mapping (QSM): decoding MRI data for a tissue magnetic biomarker

Y Wang, T Liu - Magnetic resonance in medicine, 2015 - Wiley Online Library
In MRI, the main magnetic field polarizes the electron cloud of a molecule, generating a
chemical shift for observer protons within the molecule and a magnetic susceptibility …

Cerebrovascular reactivity (CVR) MRI with CO2 challenge: a technical review

P Liu, B Jill, H Lu - Neuroimage, 2019 - Elsevier
Cerebrovascular reactivity (CVR) is an indicator of cerebrovascular reserve and provides
important information about vascular health in a range of brain conditions and diseases …

BOLD hemodynamic response function changes significantly with healthy aging

KL West, MD Zuppichini, MP Turner, DK Sivakolundu… - NeuroImage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) has been used to infer age-differences in
neural activity from the hemodynamic response function (HRF) that characterizes the blood …

Cerebral oxygen extraction fraction MRI: Techniques and applications

D Jiang, H Lu - Magnetic resonance in medicine, 2022 - Wiley Online Library
The human brain constitutes 2% of the body's total mass but uses 20% of the oxygen. The
rate of the brain's oxygen utilization can be derived from a knowledge of cerebral blood flow …

Non-BOLD contrast for laminar fMRI in humans: CBF, CBV, and CMRO2

L Huber, K Uludağ, HE Möller - Neuroimage, 2019 - Elsevier
Functional magnetic resonance imaging (fMRI) using the blood oxygenation level-
dependent (BOLD) contrast indirectly probes neuronal activity changes via evoked cerebral …

Default‐mode network functional connectivity is closely related to metabolic activity

S Passow, K Specht, TC Adamsen… - Human brain …, 2015 - Wiley Online Library
Over the last decade, the brain's default‐mode network (DMN) and its function has attracted
a lot of attention in the field of neuroscience. However, the exact underlying mechanisms of …

Quantitative mapping of cerebral metabolic rate of oxygen (CMRO2) using quantitative susceptibility mapping (QSM)

J Zhang, T Liu, A Gupta, P Spincemaille… - Magnetic resonance …, 2015 - Wiley Online Library
Purpose To quantitatively map cerebral metabolic rate of oxygen () and oxygen extraction
fraction () in human brains using quantitative susceptibility mapping (QSM) and arterial spin …

Advanced MRI techniques to improve our understanding of experience-induced neuroplasticity

CL Tardif, CJ Gauthier, CJ Steele, PL Bazin, A Schäfer… - Neuroimage, 2016 - Elsevier
Over the last two decades, numerous human MRI studies of neuroplasticity have shown
compelling evidence for extensive and rapid experience-induced brain plasticity in vivo. To …

BOLD signal physiology: models and applications

CJ Gauthier, AP Fan - Neuroimage, 2019 - Elsevier
The BOLD contrast mechanism has a complex relationship with functional brain activity,
oxygen metabolism, and neurovascular factors. Accurate interpretation of the BOLD signal …

Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults

J Cho, J Lee, H An, MS Goyal, Y Su… - Journal of Cerebral …, 2021 - journals.sagepub.com
We aimed to validate oxygen extraction fraction (OEF) estimations by quantitative
susceptibility mapping plus quantitative blood oxygen-level dependence (QSM+ qBOLD, or …