Cerebral oxygen extraction fraction (OEF): Comparison of challenge-free gradient echo QSM+qBOLD (QQ) with 15O PET in healthy adults

J Cho, J Lee, H An, MS Goyal, Y Su… - Journal of Cerebral …, 2021 - journals.sagepub.com
We aimed to validate oxygen extraction fraction (OEF) estimations by quantitative
susceptibility mapping plus quantitative blood oxygen-level dependence (QSM+ qBOLD, or …

Age‐related changes in brain hemodynamics; A calibrated MRI study

JB De Vis, J Hendrikse, A Bhogal, A Adams… - Human brain …, 2015 - Wiley Online Library
Introduction Blood oxygenation‐level dependent (BOLD) magnetic resonance imaging
signal changes in response to stimuli have been used to evaluate age‐related changes in …

Cerebral metabolic rate of oxygen (CMRO2) mapping by combining quantitative susceptibility mapping (QSM) and quantitative blood oxygenation level‐dependent …

J Cho, Y Kee, P Spincemaille… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose To map the cerebral metabolic rate of oxygen (CMRO2) by estimating the oxygen
extraction fraction (OEF) from gradient echo imaging (GRE) using phase and magnitude of …

Hearts and minds: linking vascular rigidity and aerobic fitness with cognitive aging

CJ Gauthier, M Lefort, S Mekary… - Neurobiology of …, 2015 - Elsevier
Human aging is accompanied by both vascular and cognitive changes. Although arteries
throughout the body are known to become stiffer with age, this vessel hardening is believed …

What have we learned from perfusion MRI in multiple sclerosis?

E Lapointe, DKB Li, AL Traboulsee… - American Journal of …, 2018 - Am Soc Neuroradiology
Using MR imaging, perfusion can be assessed either by dynamic susceptibility contrast MR
imaging or arterial spin-labeling. Alterations of cerebral perfusion have repeatedly been …

[HTML][HTML] Age differences in brain signal variability are robust to multiple vascular controls

DD Garrett, U Lindenberger, RD Hoge, CJ Gauthier - Scientific reports, 2017 - nature.com
A host of studies support that younger, better performing adults express greater moment-to-
moment blood oxygen level-dependent (BOLD) signal variability (SDBOLD) in various …

Cluster analysis of time evolution (CAT) for quantitative susceptibility mapping (QSM) and quantitative blood oxygen level‐dependent magnitude (qBOLD)‐based …

J Cho, S Zhang, Y Kee, P Spincemaille… - Magnetic resonance …, 2020 - Wiley Online Library
Purpose To improve the accuracy of QSM plus quantitative blood oxygen level‐dependent
magnitude (QSM+ qBOLD or QQ)‐based mapping of the oxygen extraction fraction (OEF) …

[HTML][HTML] The role of cerebrovascular-reactivity mapping in functional MRI: calibrated fMRI and resting-state fMRI

JJ Chen, CJ Gauthier - Frontiers in physiology, 2021 - frontiersin.org
Task and resting-state functional MRI (fMRI) is primarily based on the same blood-
oxygenation level-dependent (BOLD) phenomenon that MRI-based cerebrovascular …

The thermodynamics of thinking: connections between neural activity, energy metabolism and blood flow

RB Buxton - … Transactions of the Royal Society B, 2021 - royalsocietypublishing.org
Several current functional neuroimaging methods are sensitive to cerebral metabolism and
cerebral blood flow (CBF) rather than the underlying neural activity itself. Empirically, the …

[HTML][HTML] Respiratory challenge MRI: practical aspects

FC Moreton, KA Dani, C Goutcher, K O'Hare… - NeuroImage: Clinical, 2016 - Elsevier
Respiratory challenge MRI is the modification of arterial oxygen (PaO 2) and/or carbon
dioxide (PaCO 2) concentration to induce a change in cerebral function or metabolism which …