Aging is a complex biological process accompanied by a progressive decline in the physical
function of the organism and an increased risk of age-related chronic diseases such as …

Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …

Studies of DNA methylation (DNAm) in solid human tissues are relatively scarce; tissue-
specific characterization of DNAm is needed to understand its role in gene regulation and its …

An expanding range of genetic syndromes are characterized by genome‐wide disruptions in
DNA methylation profiles referred to as episignatures. Episignatures are distinct, highly …

Sedentary lifestyle and consumption of high-calorie foods have caused a relentless increase
of overweight and obesity prevalence at all ages. Its presently epidemic proportion is …

Epigenetic changes are required for normal development, yet the nature and respective
contribution of factors that drive epigenetic variation in humans remain to be fully …

Identifying genetic variants that are associated with variation in DNA methylation, an
analysis commonly referred to as methylation quantitative trait locus (meQTL) mapping, is an …

The pineal gland-derived indoleamine hormone, melatonin, regulates multiple cellular
processes, ranging from chronobiology, proliferation, apoptosis, and oxidative damage to …

Parkinson's disease (PD) is a neurodegenerative disorder with a complex etiology and
increasing prevalence worldwide. As PD is influenced by a combination of genetic and …

As environmental fluctuations are becoming more common, organisms need to rapidly adapt
to anthropogenic, climatic, and ecological changes. Epigenetic modifications and DNA …