Zebrafish larvae as a behavioral model in neuropharmacology

RM Basnet, D Zizioli, S Taweedet, D Finazzi, M Memo - Biomedicines, 2019 - mdpi.com
Zebrafish larvae show a clear and distinct pattern of swimming in response to light and dark
conditions, following the development of a swim bladder at 4 days post fertilization. This …

Circuit neuroscience in zebrafish

RW Friedrich, GA Jacobson, P Zhu - Current Biology, 2010 - cell.com
A central goal of modern neuroscience is to obtain a mechanistic understanding of higher
brain functions under healthy and diseased conditions. Addressing this challenge requires …

A cellular-resolution atlas of the larval zebrafish brain

M Kunst, E Laurell, N Mokayes, A Kramer, F Kubo… - Neuron, 2019 - cell.com
Understanding brain-wide neuronal dynamics requires a detailed map of the underlying
circuit architecture. We built an interactive cellular-resolution atlas of the zebrafish brain at 6 …

[HTML][HTML] From whole-brain data to functional circuit models: the zebrafish optomotor response

EA Naumann, JE Fitzgerald, TW Dunn, J Rihel… - Cell, 2016 - cell.com
Detailed descriptions of brain-scale sensorimotor circuits underlying vertebrate behavior
remain elusive. Recent advances in zebrafish neuroscience offer new opportunities to …

A visual pathway for looming-evoked escape in larval zebrafish

I Temizer, JC Donovan, H Baier, JL Semmelhack - Current Biology, 2015 - cell.com
Avoiding the strike of an approaching predator requires rapid visual detection of a looming
object, followed by a directed escape maneuver. While looming-sensitive neurons have …

[HTML][HTML] Whole-brain activity maps reveal stereotyped, distributed networks for visuomotor behavior

R Portugues, CE Feierstein, F Engert, MB Orger - Neuron, 2014 - cell.com
Most behaviors, even simple innate reflexes, are mediated by circuits of neurons spanning
areas throughout the brain. However, in most cases, the distribution and dynamics of firing …

A dedicated visual pathway for prey detection in larval zebrafish

JL Semmelhack, JC Donovan, TR Thiele, E Kuehn… - Elife, 2014 - elifesciences.org
Zebrafish larvae show characteristic prey capture behavior in response to small moving
objects. The neural mechanism used to recognize objects as prey remains largely unknown …

Functional neuronal circuits emerge in the absence of developmental activity

DL Barabási, GFP Schuhknecht, F Engert - Nature Communications, 2024 - nature.com
The complex neuronal circuitry of the brain develops from limited information contained in
the genome. After the genetic code instructs the birth of neurons, the emergence of brain …

Visual prey capture in larval zebrafish is controlled by identified reticulospinal neurons downstream of the tectum

E Gahtan, P Tanger, H Baier - Journal of Neuroscience, 2005 - Soc Neuroscience
Many vertebrates are efficient hunters and recognize their prey by innate neural
mechanisms. During prey capture, the internal representation of the prey's location must be …

Neural control and modulation of swimming speed in the larval zebrafish

KE Severi, R Portugues, JC Marques, DM O'Malley… - Neuron, 2014 - cell.com
Vertebrate locomotion at different speeds is driven by descending excitatory connections to
central pattern generators in the spinal cord. To investigate how these inputs determine …