[HTML][HTML] Role of extracellular vesicles as potential diagnostic and/or therapeutic biomarkers in chronic cardiovascular diseases

JL Martin-Ventura, C Roncal, J Orbe… - Frontiers in Cell and …, 2022 - frontiersin.org
Cardiovascular diseases (CVDs) are the first cause of death worldwide. In recent years,
there has been great interest in the analysis of extracellular vesicles (EVs), including …

[HTML][HTML] Circulating biomarkers for the prediction of abdominal aortic aneurysm growth

P Nana, K Dakis, A Brodis, K Spanos… - Journal of Clinical …, 2021 - mdpi.com
Background: Abdominal aortic aneurysm represents a distinct group of vascular lesions, in
terms of surveillance and treatment. Screening and follow-up of patients via duplex …

Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm

R Roldán-Montero, JM Pérez-Sáez, I Cerro-Pardo… - Science …, 2022 - science.org
Pathological vascular remodeling is the underlying cause of atherosclerosis and abdominal
aortic aneurysm (AAA). Here, we analyzed the role of galectin-1 (Gal-1), a β-galactoside …

Targeting mitochondrial stress with Szeto‐Schiller 31 prevents experimental abdominal aortic aneurysm: Crosstalk with endoplasmic reticulum stress

M Navas‐Madroñal… - British Journal of …, 2023 - Wiley Online Library
Abstract Background and Purpose Mitochondrial dysfunction and inflammation contribute to
a myriad of cardiovascular diseases. Deleterious crosstalk of mitochondria and persistent …

[HTML][HTML] The important role of endothelium and extracellular vesicles in the cellular mechanism of aortic aneurysm formation

K Mikołajczyk, D Spyt, W Zielińska, A Żuryń… - International journal of …, 2021 - mdpi.com
Homeostasis is a fundamental property of biological systems consisting of the ability to
maintain a dynamic balance of the environment of biochemical processes. The action of …

[HTML][HTML] APOA1 oxidation is associated to dysfunctional high-density lipoproteins in human abdominal aortic aneurysm

D Martínez-López, E Camafeita, L Cedó… - …, 2019 - thelancet.com
Background High-density lipoproteins (HDL) are a complex mixture of lipids and proteins
with vasculoprotective properties. However, HDL components could suffer post-translational …

[HTML][HTML] Rolipram prevents the formation of abdominal aortic aneurysm (AAA) in mice: PDE4B as a target in AAA

S Varona, L Puertas, M Galán, M Orriols, L Cañes… - Antioxidants, 2021 - mdpi.com
Abdominal aortic aneurysm (AAA) is a common life-threatening condition characterized by
exacerbated inflammation and the generation of reactive oxygen species. Pharmacological …

[HTML][HTML] NR4A3: a key nuclear receptor in vascular biology, cardiovascular remodeling, and beyond

J Martínez-González, L Cañes, J Alonso… - International journal of …, 2021 - mdpi.com
The mechanisms committed in the activation and response of vascular and inflammatory
immune cells play a major role in tissue remodeling in cardiovascular diseases (CVDs) such …

Identification of circ-FNDC3B, an overexpressed circRNA in abdominal aortic aneurysm, as a regulator of vascular smooth muscle cells

Y Liu, Z Zhong, L Xiao, W Li, Z Wang… - International Heart …, 2021 - jstage.jst.go.jp
Circular RNAs (circRNAs) have been implicated in the dysfunction of vascular smooth
muscle cells (VSMCs), which is linked with the development of abdominal aortic aneurysm …

[HTML][HTML] Protection of diabetes in aortic abdominal aneurysm: Are antidiabetics the real effectors?

B Picatoste, I Cerro-Pardo, LM Blanco-Colio… - Frontiers in …, 2023 - frontiersin.org
Aortic aneurysms, including abdominal aortic aneurysms (AAAs), is the second most
prevalent aortic disease and represents an important cause of death worldwide. AAA is a …