Systemic hypertension at high altitude

O Narvaez-Guerra, K Herrera-Enriquez… - …, 2018 - Am Heart Assoc
568 Hypertension September 2018 prevalence of hypertension with a 2% increase for
every≈ 100 m (≈ 330 ft)-increase in altitude above 3000 mASL (≈ 9800 ft). 16 …

[HTML][HTML] The brain at high altitude: from molecular signaling to cognitive performance

MA Aboouf, M Thiersch, J Soliz, M Gassmann… - International Journal of …, 2023 - mdpi.com
The brain requires over one-fifth of the total body oxygen demand for normal functioning. At
high altitude (HA), the lower atmospheric oxygen pressure inevitably challenges the brain …

Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution

JS Heng, A Rattner, GL Stein-O'Brien… - Proceedings of the …, 2019 - National Acad Sciences
The mammalian CNS is capable of tolerating chronic hypoxia, but cell type-specific
responses to this stress have not been systematically characterized. In the Norrin KO (Ndp …

[图书][B] Ward, Milledge and West's High altitude medicine and physiology

AM Luks, PN Ainslie, JS Lawley, RC Roach… - 2021 - taylorfrancis.com
This pre-eminent work has developed over six editions in response to man's attempts to
climb higher and higher unaided, and to spend more time at altitude for both work and …

[HTML][HTML] The human brain in a high altitude natural environment: A review

X Zhang, J Zhang - Frontiers in Human Neuroscience, 2022 - frontiersin.org
With the advancement of in vivo magnetic resonance imaging (MRI) technique, more
detailed information about the human brain at high altitude (HA) has been revealed. The …

[HTML][HTML] Resting-state neuronal activity and functional connectivity changes in the visual cortex after high altitude exposure: a longitudinal study

X Zhang, T Kang, Y Liu, F Yuan, M Li, J Lin, J Zhang - Brain Sciences, 2022 - mdpi.com
Damage to the visual cortex structures after high altitude exposure has been well clarified.
However, changes in the neuronal activity and functional connectivity (FC) of the visual …

[HTML][HTML] Consistent differences in brain structure and functional connectivity in high-altitude native Tibetans and immigrants

X Zhang, W Xie, W Du, Y Liu, J Lin, W Yin… - Brain Imaging and …, 2023 - Springer
It has been well-established that high-altitude (HA) environments affect the human brain;
however, the differences in brain structural and functional networks between HA natives and …

[HTML][HTML] Effects of weather and season on human brain volume

GA Book, SA Meda, R Janssen, AD Dager, A Poppe… - PLoS …, 2021 - journals.plos.org
We present an exploratory cross-sectional analysis of the effect of season and weather on
Freesurfer-derived brain volumes from a sample of 3,279 healthy individuals collected on …

Brain structural and functional alterations in native Tibetans living at high altitude

X Zhang, W Xie, Y Liu, M Li, J Lin, W Yin, L Yang, P Li… - Neuroscience, 2023 - Elsevier
Tibetans have adapted to high altitude environments. However, the genetic effects in their
brains have not been identified. Twenty-five native Tibetans living in Lhasa (3650 m) were …

[HTML][HTML] Chronic exposure to high altitude: synaptic, astroglial and memory changes

R Sharma, NP Cramer, B Perry, Z Adahman… - Scientific Reports, 2019 - nature.com
Long-term operations carried out at high altitude (HA) by military personnel, pilots, and
astronauts may trigger health complications. In particular, chronic exposure to high altitude …