Epigenetic drug discovery field has evidenced significant advancement in the recent times.
A plethora of small molecule inhibitors have progressed to clinical stage investigations and …

Neoplastic cells simultaneously harbor widespread genomic hypomethylation, more
regional areas of hypermethylation, and increased DNA-methyltransferase (DNA-MTase) …

Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

This book explores the socio-political implications of human heredity from the second half of
the nineteenth century to the present postgenomic moment. It addresses three main phases …

Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

The synthetic estrogen diethylstilbestrol (DES) is a potent perinatal endocrine disruptor. In
humans and experimental animals, exposure to DES during critical periods of reproductive …

Researchers in the field of molecular ecology and evolution require versatile and low‐cost
genetic typing methods. The AFLP (amplified fragment length polymorphism) method was …

Late-flowering ecotypes and mutants of Arabidopsis thaliana and the related crucifer Thlaspi
arvense flower early after cold treatment (vernalization). Treatment with the DNA …

The death, in 1996, of science historian and philosopher, Thomas Kuhn, and the publication
of the a new edition of The Structure of Scientific Revolutions (3 Edn., Univ. Chicago Press …

AFLP analysis using restriction enzyme isoschizomers that differ in their sensitivity to
methylation of their recognition sites has been used to analyse the methylation state of …