The present study established a novel and reproducible animal model to study abdominal
aortic aneurysms. In total, 22 adult Lewis rats underwent a procedure to produce mechanical …

Aims: The precise molecular drivers of abdominal aortic aneurysm (AAA) remain unclear.
Thymidine phosphorylase (TYMP) contributes to increased platelet activation, thrombosis …

The pathogenesis of the aortic aneurysm (AA) includes several mechanisms, such as
chronic sterile inflammation and homeostasis imbalance, with arteriosclerosis …

Animal models have significantly contributed to our understanding of vascular biology and
cardiac function over the last century. In fact, pioneering experimental models such as the …

Vascular Surgery: A Clinical Guide to Decision-making is a concise but comprehensive
resource for operating vascular surgeons and clinicians. It serves as an essential reference …

An abdominal aortic aneurysm (AAA) is a life-threatening cardiovascular disease that occurs
worldwide and is characterized by irreversible dilation of the abdominal aorta. Currently …

Previous abdominal aortic aneurysm (AAA) animal modeling methodologies were either
expensive or complicated. Here, we developed a novel AAA model which was simple to set …

目的探讨醋酸脱氧皮质酮(DOCA) 加高盐在不同时间点对腹主动脉瘤的诱导作用,
及潜在分子机制. 方法将10 月龄C57BL/6J 小鼠分为两组: 高盐组(HS), DOCA …

The association between gene variant rs7635818 located on chromosome 3p12. 3 and
abdominal aortic aneurysm (AAA) was not unambiguously determined by the results of …

Background: Hepcidin is a liver-derived hormone that controls systemic iron homeostasis, by
inhibiting the iron exporter ferroportin in the gut and spleen, respective sites of iron …