Defects in apoptotic pathway contribute to uncontrolled proliferation of cancer cells and
confer resistance to chemotherapy. Growth arrest and DNA damage inducible, alpha …

BACKGROUND Multiple diverse posttranslational modifications of α‐tubulin such as
detyrosination, further cleavage of the penultimate glutamate residue (Δ2‐tubulin) …

About 70% of breast tumors express estrogen receptor alpha (ERα), which mediates the
proliferative effects of estrogens on breast epithelial cells, and are candidates for treatment …

Prostate cancer is one of the most frequent cancers in males in Western industrialized
countries. Its course is highly variable, from indolent to highly lethal. Genetic changes vary …

This study was conducted to investigate the promoter methylation status of the p16, DAPK,
CDH1, and TIMP-3 genes in primary cervical cancer and its correlation with …

Research on cancer epigenetics has flourished in the last decade. Nevertheless growing
evidence point on the importance to understand the mechanisms by which epigenetic …

BACKGROUND We previously demonstrated that a putative anti‐tumor gene, peroxisomal
membrane protein 4, 24 kDa (PMP24 or PXMP4), is silenced via DNA methylation of a CpG …

The aim of the present study was to investigate the correlation between the expression of
DNA (cytosine‑5)‑methyltransferase 1 (DNMT1), glutathione S‑transferase‑P1 (GSTP1) and …

Abstract DNA (cytosine-5-carbon) methylation is one of the hallmarks of mammalian
chromatin modifications. Distinct methylation pattern can generate synergistic or …

Objective The Death-Associated Protein Kinase 1 (DAPK1) gene has been frequently
investigated in cervical cancer (CC). The aim of the present study was to carry out a …