[HTML][HTML] Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in …
Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity
through levels of biological organization. By determining the linkages between toxicity …
through levels of biological organization. By determining the linkages between toxicity …
Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity
J Legradi, N El Abdellaoui, M Van Pomeren… - … Science and Pollution …, 2015 - Springer
Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …
has been shown that neurological disorders like autism may be related to chemical …
Polystyrene nanoplastic exposure induces developmental toxicity by activating the oxidative stress response and base excision repair pathway in zebrafish (Danio …
M Feng, J Luo, Y Wan, J Zhang, C Lu, M Wang… - ACS …, 2022 - ACS Publications
The widespread accumulation of nanoplastics is a growing concern for the environmental
and human health. However, studies on the mechanisms of nanoplastic-induced …
and human health. However, studies on the mechanisms of nanoplastic-induced …
Behavioral and biochemical consequences of Danio rerio larvae exposure to polylactic acid bioplastic
JPJ de Oliveira, FN Estrela… - Journal of hazardous …, 2021 - Elsevier
The literature has largely shown the toxicity of petroleum-based PLA biomicroplastics
(PLABioMPs) and encouraged the production of alternative materials to replace their use …
(PLABioMPs) and encouraged the production of alternative materials to replace their use …
Adult Zebrafish (Danio rerio): An Alternative Behavioral Model of Formalin-Induced Nociception
FEA Magalhães, CÁPB de Sousa, SAAR Santos… - Zebrafish, 2017 - liebertpub.com
The zebrafish (Danio rerio) has been proposed as a low-cost and simple alternative to the
use of higher vertebrates in laboratory research on novel compounds with antinociceptive …
use of higher vertebrates in laboratory research on novel compounds with antinociceptive …
Behavioral, morphometric, and gene expression effects in adult zebrafish (Danio rerio) embryonically exposed to PFOA, PFOS, and PFNA
CE Jantzen, KM Annunziato, KR Cooper - Aquatic toxicology, 2016 - Elsevier
Perfluoroalkylated substances (PFAS) are a class of persistent anthropogenic chemicals that
have been detected worldwide. PFASs consist of fluorinated carbon chains of varying …
have been detected worldwide. PFASs consist of fluorinated carbon chains of varying …
Maternal cortisol stimulates neurogenesis and affects larval behaviour in zebrafish
Excess glucocorticoid transferred from stressed mother to the embryo affects developing
vertebrate offspring, but the underlying programming events are unclear. In this study, we …
vertebrate offspring, but the underlying programming events are unclear. In this study, we …
The brilliance of the zebrafish model: perception on behavior and Alzheimer's disease
A Shenoy, M Banerjee, A Upadhya… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) has become increasingly prevalent in the elderly population
across the world. It's pathophysiological markers such as overproduction along with the …
across the world. It's pathophysiological markers such as overproduction along with the …
Environmentally relevant concentrations of triclocarban affect behaviour, learning, and brain gene expression in fish
T Lucon-Xiccato, BB Savaşçı, C Merola… - Science of The Total …, 2023 - Elsevier
Many chemicals spilled in aquatic ecosystems can interfere with cognitive abilities and brain
functions that control fitness-related behaviour. Hence, their harmful potential may be …
functions that control fitness-related behaviour. Hence, their harmful potential may be …
Zebrafish as an animal model for testing agents with antidepressant potential
J Lachowicz, K Niedziałek, E Rostkowska, A Szopa… - Life, 2021 - mdpi.com
Depression is a serious mental disease that, according to statistics, affects 320 million
people worldwide. Additionally, a current situation related to the COVID-19 pandemic has …
people worldwide. Additionally, a current situation related to the COVID-19 pandemic has …