[HTML][HTML] Development and application of the adverse outcome pathway framework for understanding and predicting chronic toxicity: II. A focus on growth impairment in …

KJ Groh, RN Carvalho, JK Chipman, ND Denslow… - Chemosphere, 2015 - Elsevier
Adverse outcome pathways (AOPs) organize knowledge on the progression of toxicity
through levels of biological organization. By determining the linkages between toxicity …

Comparability of behavioural assays using zebrafish larvae to assess neurotoxicity

J Legradi, N El Abdellaoui, M Van Pomeren… - … Science and Pollution …, 2015 - Springer
Testing of compounds for neurotoxicity has become increasingly important in recent years. It
has been shown that neurological disorders like autism may be related to chemical …

Polystyrene nanoplastic exposure induces developmental toxicity by activating the oxidative stress response and base excision repair pathway in zebrafish (Danio …

M Feng, J Luo, Y Wan, J Zhang, C Lu, M Wang… - ACS …, 2022 - ACS Publications
The widespread accumulation of nanoplastics is a growing concern for the environmental
and human health. However, studies on the mechanisms of nanoplastic-induced …

Behavioral and biochemical consequences of Danio rerio larvae exposure to polylactic acid bioplastic

JPJ de Oliveira, FN Estrela… - Journal of hazardous …, 2021 - Elsevier
The literature has largely shown the toxicity of petroleum-based PLA biomicroplastics
(PLABioMPs) and encouraged the production of alternative materials to replace their use …

Adult Zebrafish (Danio rerio): An Alternative Behavioral Model of Formalin-Induced Nociception

FEA Magalhães, CÁPB de Sousa, SAAR Santos… - Zebrafish, 2017 - liebertpub.com
The zebrafish (Danio rerio) has been proposed as a low-cost and simple alternative to the
use of higher vertebrates in laboratory research on novel compounds with antinociceptive …

Behavioral, morphometric, and gene expression effects in adult zebrafish (Danio rerio) embryonically exposed to PFOA, PFOS, and PFNA

CE Jantzen, KM Annunziato, KR Cooper - Aquatic toxicology, 2016 - Elsevier
Perfluoroalkylated substances (PFAS) are a class of persistent anthropogenic chemicals that
have been detected worldwide. PFASs consist of fluorinated carbon chains of varying …

Maternal cortisol stimulates neurogenesis and affects larval behaviour in zebrafish

C Best, DM Kurrasch, MM Vijayan - Scientific reports, 2017 - nature.com
Excess glucocorticoid transferred from stressed mother to the embryo affects developing
vertebrate offspring, but the underlying programming events are unclear. In this study, we …

The brilliance of the zebrafish model: perception on behavior and Alzheimer's disease

A Shenoy, M Banerjee, A Upadhya… - Frontiers in …, 2022 - frontiersin.org
Alzheimer's disease (AD) has become increasingly prevalent in the elderly population
across the world. It's pathophysiological markers such as overproduction along with the …

Environmentally relevant concentrations of triclocarban affect behaviour, learning, and brain gene expression in fish

T Lucon-Xiccato, BB Savaşçı, C Merola… - Science of The Total …, 2023 - Elsevier
Many chemicals spilled in aquatic ecosystems can interfere with cognitive abilities and brain
functions that control fitness-related behaviour. Hence, their harmful potential may be …

Zebrafish as an animal model for testing agents with antidepressant potential

J Lachowicz, K Niedziałek, E Rostkowska, A Szopa… - Life, 2021 - mdpi.com
Depression is a serious mental disease that, according to statistics, affects 320 million
people worldwide. Additionally, a current situation related to the COVID-19 pandemic has …