[HTML][HTML] Mechanisms of resistance and current treatment options for glioblastoma multiforme (GBM)

SSK Yalamarty, N Filipczak, X Li, MA Subhan… - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme is one of the hardest-to-treat brain tumors, often
resistant to conventional treatments such as chemotherapy and radiation therapy. Despite …

[HTML][HTML] Role of glioblastoma stem cells in cancer therapeutic resistance: A perspective on antineoplastic agents from natural sources and chemical derivatives

ALV Alves, INF Gomes, AC Carloni, MN Rosa… - Stem Cell Research & …, 2021 - Springer
Glioblastoma (GBM) is the highest-grade form of glioma, as well as one of the most
aggressive types of cancer, exhibiting rapid cellular growth and highly invasive behavior …

Targeted liposomes for combined delivery of artesunate and temozolomide to resistant glioblastoma

M Ismail, W Yang, Y Li, T Chai, D Zhang, Q Du… - Biomaterials, 2022 - Elsevier
The effective treatment of glioblastoma (GBM) is a great challenge because of the blood-
brain barrier (BBB) and the growing resistance to single-agent therapeutics. Targeted …

[HTML][HTML] Impact of PEGylated liposomal doxorubicin and carboplatin combination on glioblastoma

M Ghaferi, A Raza, M Koohi, W Zahra, A Akbarzadeh… - Pharmaceutics, 2022 - mdpi.com
Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%.
Chemotherapy is a therapeutic approach to treating the disease; however, due to the …

Recent advances in drug delivery systems for targeting brain tumors

Y Zhao, P Yue, Y Peng, Y Sun, X Chen, Z Zhao… - Drug delivery, 2023 - Taylor & Francis
Brain tumor accounts for about 1.6% of incidence and 2.5% of mortality of all tumors, and the
median survival for brain tumor patients is only about 20 months. The treatment for brain …

Benefits and limitations of nanomedicine treatment of brain cancers and age-dependent neurodegenerative disorders

ME Neganova, YR Aleksandrova… - Seminars in Cancer …, 2022 - Elsevier
The treatment of central nervous system (CNS) malignancies, including brain cancers, is
limited by a number of obstructions, including the blood-brain barrier (BBB), the …

Polymeric nanoparticles for drug delivery in glioblastoma: State of the art and future perspectives

F Madani, SS Esnaashari, TJ Webster… - Journal of Controlled …, 2022 - Elsevier
Glioblastoma (GBM) is an aggressive, fatal and malignant primary brain tumor. Despite the
current standard treatment for glioblastoma patients including neurosurgical resection …

Upconversion nanoparticle-based cell membrane-coated cRGD peptide bioorthogonally labeled nanoplatform for glioblastoma treatment

J Mo, X Chen, M Li, W Liu, W Zhao, LY Lim… - … applied materials & …, 2022 - ACS Publications
Glioblastoma is hard to be eradicated partly because of the obstructive blood–brain barrier
(BBB) and the dynamic autophagy activities of glioblastoma. Here, hydroxychloroquine …

[HTML][HTML] Role of nanomedicine-based therapeutics in the treatment of CNS disorders

ZH Guo, S Khattak, MA Rauf, MA Ansari, MN Alomary… - Molecules, 2023 - mdpi.com
Central nervous system disorders, especially neurodegenerative diseases, are a public
health priority and demand a strong scientific response. Various therapy procedures have …

[HTML][HTML] Targeting glioblastoma stem cells to overcome chemoresistance: an overview of current therapeutic strategies

H Kang, H Lee, D Kim, B Kim, JH Kang, HY Kim… - Biomedicines, 2022 - mdpi.com
Glioblastoma (GBM) is the most malignant primary brain tumor. The current standard
approach in GBM is surgery, followed by treatment with radiation and temozolomide (TMZ); …