In recent years, the zebrafish has become one of the most prominent vertebrate model
organisms used to study the genetics underlying development, normal body function, and …

In recent years, the zebrafish has become a favourite model organism for biologists studying
developmental processes in vertebrates. Its rapid embryonic development, the transparency …

Glia-axon interactions are essential for the development and function of the nervous system.
We combine in vivo imaging and genetics to address the mechanism by which the migration …

Background: Patterned growth of vertebrate organs is essential for normal physiological
function, but the underlying pathways that govern organotypic growth are not clearly …

Post-transcriptional regulation of gene expression occurs by multiple mechanisms, including
subcellular localization of mRNA and alteration of the poly (A) tail length. These …

Background In many animals, germ cells are set aside from somatic cells early during
development to give rise to sperm in males and eggs in females. One strategy to achieve …

Zebrafish gastrulation entails morphogenetic cell movements that shape the body plan and
give rise to an embryo with defined anterior–posterior and dorsal–ventral axes. Regulating …

Whole genome comparisons of distantly related species effectively predict biologically
important sequences—core genes and cis-acting regulatory elements (REs)—but require …

Key to invasiveness is the ability of tumor cells to modify the extracellular matrix, become
motile, and engage in directed migration towards the vasculature. One significant protein …

Zebrafish gastrulation cell movements occur in the context of dynamic changes in
extracellular matrix (ECM) organization and require the concerted action of planar cell …