Multiplexed profiling of extracellular vesicles for biomarker development
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …
A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery
I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …
processes such as cell proliferation or intercellular communication. Recently, exosomes …
A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles
G Zhang, Y Wang, W Zhou, Y Lei, J Lu… - Angewandte …, 2023 - Wiley Online Library
The protein phenotypes of extracellular vesicles (EVs) have emerged as promising
biomarkers for cancer diagnosis and treatment monitoring. However, the technical …
biomarkers for cancer diagnosis and treatment monitoring. However, the technical …
Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …
into their role and significance in human health. Exosomes derived from various sources …
[HTML][HTML] Advances in the analysis of single extracellular vesicles: A critical review
SH Hilton, IM White - Sensors and actuators reports, 2021 - Elsevier
There is an ever-growing need for new cancer diagnostic approaches that provide earlier
diagnosis as well as richer diagnostic, prognostic, and resistance information. Extracellular …
diagnosis as well as richer diagnostic, prognostic, and resistance information. Extracellular …
[HTML][HTML] The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design
This work addresses a biosensor combining the immunomagnetic separation and the
electrochemical biosensing based on the intrinsic ALP activity of the exosomes. This …
electrochemical biosensing based on the intrinsic ALP activity of the exosomes. This …
Carbon-based biosensors from graphene family to carbon dots: A viewpoint in cancer detection
According to the latest report by International Agency for Research on Cancer, 19.3 million
new cancer cases and 10 million cancer deaths were globally reported in 2020. Early …
new cancer cases and 10 million cancer deaths were globally reported in 2020. Early …
All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model
K Chattrairat, T Yasui, S Suzuki, A Natsume… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) have promising potential as biomarkers for early cancer
diagnosis. The EVs have been widely studied as biological cargo containing essential …
diagnosis. The EVs have been widely studied as biological cargo containing essential …
Emerging multianalyte biosensors for the simultaneous detection of protein and nucleic acid biomarkers
Traditionally, biosensors are designed to detect one specific analyte. Nevertheless, disease
progression is regulated in a highly interactive way by different classes of biomolecules like …
progression is regulated in a highly interactive way by different classes of biomolecules like …
Review of the advances in lipid anchors-based biosensors for the isolation and detection of exosomes
J Zheng, X Hu, Y Zeng, B Zhang, Z Sun, X Liu… - Analytica Chimica …, 2023 - Elsevier
Exosomes are nanoparticles with a bilayer lipid structure that carry cargo from their cells of
origin. These vesicles are vital to disease diagnosis and therapeutics; however …
origin. These vesicles are vital to disease diagnosis and therapeutics; however …