Multiplexed profiling of extracellular vesicles for biomarker development

C Jiang, Y Fu, G Liu, B Shu, J Davis, GK Tofaris - Nano-micro letters, 2022 - Springer
Extracellular vesicles (EVs) are cell-derived membranous particles that play a crucial role in
molecular trafficking, intercellular transport and the egress of unwanted proteins. They have …

A guide to mass spectrometric analysis of extracellular vesicle proteins for biomarker discovery

I Jalaludin, DM Lubman, J Kim - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Exosomes (small extracellular vesicles) in living organisms play an important role in
processes such as cell proliferation or intercellular communication. Recently, exosomes …

A Magnetically Driven Tandem Chip Enables Rapid Isolation and Multiplexed Profiling of Extracellular Vesicles

G Zhang, Y Wang, W Zhou, Y Lei, J Lu… - Angewandte …, 2023 - Wiley Online Library
The protein phenotypes of extracellular vesicles (EVs) have emerged as promising
biomarkers for cancer diagnosis and treatment monitoring. However, the technical …

Biogenesis, isolation, and detection of exosomes and their potential in therapeutics and Diagnostics

S Sonbhadra, Mehak, LM Pandey - Biosensors, 2023 - mdpi.com
The increasing research and rapid developments in the field of exosomes provide insights
into their role and significance in human health. Exosomes derived from various sources …

[HTML][HTML] Advances in the analysis of single extracellular vesicles: A critical review

SH Hilton, IM White - Sensors and actuators reports, 2021 - Elsevier
There is an ever-growing need for new cancer diagnostic approaches that provide earlier
diagnosis as well as richer diagnostic, prognostic, and resistance information. Extracellular …

[HTML][HTML] The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design

SL Moura, A Pallarès-Rusiñol, L Sappia, M Martí… - Biosensors and …, 2022 - Elsevier
This work addresses a biosensor combining the immunomagnetic separation and the
electrochemical biosensing based on the intrinsic ALP activity of the exosomes. This …

Carbon-based biosensors from graphene family to carbon dots: A viewpoint in cancer detection

M Safari, A Moghaddam, AS Moghaddam, M Absalan… - Talanta, 2023 - Elsevier
According to the latest report by International Agency for Research on Cancer, 19.3 million
new cancer cases and 10 million cancer deaths were globally reported in 2020. Early …

All-in-One Nanowire Assay System for Capture and Analysis of Extracellular Vesicles from an ex Vivo Brain Tumor Model

K Chattrairat, T Yasui, S Suzuki, A Natsume… - ACS …, 2023 - ACS Publications
Extracellular vesicles (EVs) have promising potential as biomarkers for early cancer
diagnosis. The EVs have been widely studied as biological cargo containing essential …

Emerging multianalyte biosensors for the simultaneous detection of protein and nucleic acid biomarkers

A Klebes, HC Ates, RD Verboket, GA Urban… - Biosensors and …, 2023 - Elsevier
Traditionally, biosensors are designed to detect one specific analyte. Nevertheless, disease
progression is regulated in a highly interactive way by different classes of biomolecules like …

Review of the advances in lipid anchors-based biosensors for the isolation and detection of exosomes

J Zheng, X Hu, Y Zeng, B Zhang, Z Sun, X Liu… - Analytica Chimica …, 2023 - Elsevier
Exosomes are nanoparticles with a bilayer lipid structure that carry cargo from their cells of
origin. These vesicles are vital to disease diagnosis and therapeutics; however …