[HTML][HTML] 5-methylcytosine turnover: Mechanisms and therapeutic implications in cancer

M Turpin, G Salbert - Frontiers in Molecular Biosciences, 2022 - frontiersin.org
DNA methylation at the fifth position of cytosine (5mC) is one of the most studied epigenetic
mechanisms essential for the control of gene expression and for many other biological …

[HTML][HTML] Circadian clock regulator Bmal1 gates axon regeneration via Tet3 epigenetics in mouse sensory neurons

D Halawani, Y Wang, A Ramakrishnan, M Estill… - Nature …, 2023 - nature.com
Axon regeneration of dorsal root ganglia (DRG) neurons after peripheral axotomy involves
reconfiguration of gene regulatory circuits to establish regenerative gene programs …

Experience with German Research Consortia in the Field of Chemical Biology of Native Nucleic Acid Modifications

M Helm, MT Bohnsack, T Carell, A Dalpke… - ACS Chemical …, 2023 - ACS Publications
The chemical biology of native nucleic acid modifications has seen an intense upswing, first
concerning DNA modifications in the field of epigenetics and then concerning RNA …

Using NMR to monitor TET-dependent methylcytosine dioxygenase activity and regulation

CJ Treadway, JA Boyer, S Yang, H Yang… - ACS chemical …, 2024 - ACS Publications
The active removal of DNA methylation marks is governed by the ten-eleven translocation
(TET) family of enzymes (TET1–3), which iteratively oxidize 5-methycytosine (5mC) into 5 …

[HTML][HTML] DNA methylation-based high-resolution mapping of long-distance chromosomal interactions in nucleosome-depleted regions

Y Li, J Lee, L Bai - Nature Communications, 2024 - nature.com
Abstract 3C-based methods have significantly advanced our understanding of 3D genome
organization. However, it remains a formidable task to precisely capture long-range …

Recent Advances on DNA Base Flipping: A General Mechanism for Writing, Reading, and Erasing DNA Modifications

R Ren, JR Horton, S Hong, X Cheng - DNA Methyltransferases-Role and …, 2022 - Springer
The modification of DNA bases is a classic hallmark of epigenetics. Four forms of modified
cytosine—5-methylcytosine, 5-hydroxymethylcytosine, 5-formylcytosine, and 5 …

An Overview of Global, Local, and Base-Resolution Methods for the Detection of 5-Hydroxymethylcytosine in Genomic DNA

N Erlitzki, RM Kohli - Epigenome Editing: Methods and Protocols, 2024 - Springer
Abstract The discovery of 5-hydroxymethylcytosine (5hmC) as a common DNA modification
in mammalian genomes has ushered in new areas of inquiry regarding the dynamic …

Comparing methylation levels assayed in GC-rich regions with current and emerging methods

D Guanzon, JP Ross, C Ma, O Berry, YJ Liew - bioRxiv, 2023 - biorxiv.org
DNA methylation is an epigenetic mechanism that regulates gene expression, and for
mammals typically occurs on cytosines within CpG dinucleotides. A significant challenge for …

and Xiaodong Cheng

R Ren, JR Horton, S Hong - DNA Methyltransferases-Role and …, 2022 - books.google.com
and Xiaodong Cheng Page 300 Abstract 12 Recent Advances on DNA Base Flipping: A
General Mechanism for Writing, Reading, and Erasing DNA Modifications Ren Ren, John R …

Investigation of DNA methylation turnover in pluripotency and early differentiation

L Haut - 2023 - refubium.fu-berlin.de
Throughout embryonic development, cells undergo a series of lineage decisions,
accompanied by morphological and functional changes, culminating in the formation of a …