Patients suffering from psychiatric disorders have a life span burden, which represents an
enormous human, family, social, and economical cost. Several concepts have revolutionized …

Purpose. SOST gene is one of the key factors in regulating bone absorption. Although there
are reports showing diverse transcription factors, epigenetic modification could be …

Suboptimal environmental conditions during development can substantially alter the
epigenome. Stable environmentally-induced changes to the germline epigenome, in …

Epigenetic modifications, including DNA methylation, covalent histone modifications, and
small noncoding RNAs, play a key role in regulating the gene expression. This regulatory …

Locus-specific analyses of DNA methylation patterns usually require a bisulfite conversion of
the DNA, where cytosines are deaminated to uracils, while methylated and …

In the era of precision oncology, identifying abnormal genetic and epigenetic alterations has
transformed the way cancer is diagnosed, managed, and treated. 5-hydroxymethylcytosine …

The neural cell adhesion molecule (NCAM) is the major carrier of polysialic acid (PSA)
which modulates NCAM functions of neural cells at the cell surface. In previous studies, we …

Corticospinal motor neurons (CSMN) are an indispensable neuron population for the motor
neuron circuitry. They are excitatory projection neurons, which collect information from …

¿ Puedo heredar las enfermedades de mis padres o abuelos?¿ Es posible que mis hijos
hereden las mías?¿ Hasta qué punto una disciplina como la epigenética puede tener …

During development, the α-and β-globin genes exhibit a highly conserved pattern of
expression, giving rise to several developmental stage-specific hemoglobin variants …