DNA provides the fundamental framework for heritability, yet heritable trait variation need not
be completely 'hard-wired'into the DNA sequence. In plants, the epigenetic machinery that …

Key message Our review has described principles and functional importance of CRISPR-
Cas9 with emphasis on the recent advancements, such as CRISPR-Cpf1, base editing (BE) …

The fascination produced by the possibility of engineering plants with augmented
capabilities has accompanied plant biotechnology since its origins. This prospect has …

Tools for sequence-specific DNA binding have opened the door to new approaches in
investigating fundamental questions in biology and crop development. While there are …

Gene expression differences between distinct cell types are orchestrated by specific sets of
transcription factors and epigenetic regulators acting upon the genome. In plants, the …

Plant breeding relies on crossing-over to create novel combinations of alleles needed to
confer increased productivity and other desired traits in new varieties. However, crossover …

DNA methylation mediates silencing of transposable elements and genes in part via
recruitment of the Arabidopsis MBD5/6 complex, which contains the methyl-CpG binding …

Epigenetics is defined as changes in gene expression that are not associated with changes
in DNA sequence but due to the result of methylation of DNA and post-translational …

Over the past decade, CRISPR-Cas systems have become indispensable tools for genetic
engineering and have been used in clinical trials for various diseases. Beyond genome …

Plants have evolved with various effective mechanisms to defend themselves against
herbivores, and one such mechanism is the production of protease inhibitors that disrupt …