Natural climbers: Insights from avian physiology at high altitude

N Parr, M Wilkes, LA Hawkes - High Altitude Medicine & Biology, 2019 - liebertpub.com
High altitudes are physiologically challenging: the hypobaric hypoxia, cold, and increased
ultraviolet radiation mean humans ascending to high altitude faster than they acclimatize risk …

Establishment of an experimental rat model of high altitude cerebral edema by hypobaric hypoxia combined with temperature fluctuation

L Jing, N Wu, L He, J Shao, H Ma - Brain Research Bulletin, 2020 - Elsevier
High altitude cerebral edema (HACE) is a kind of life threat disease encountered at high
altitude, but the precise pathogenesis of it is far more understood. Hypobaic hypoxia (HH) …

Adenosine receptor-dependent signaling is not obligatory for normobaric and hypobaric hypoxia-induced cerebral vasodilation in humans

RL Hoiland, AR Bain, MM Tymko… - Journal of Applied …, 2017 - journals.physiology.org
Hypoxia increases cerebral blood flow (CBF) with the underlying signaling processes
potentially including adenosine. A randomized, double-blinded, and placebo-controlled …

Visualization of cortical cerebral blood flow dynamics during craniotomy in acute subdural hematoma using laser speckle imaging in a rat model

C Wang, L Xian, X Chen, Z Li, Y Fang, W Xu, L Wei… - Brain research, 2020 - Elsevier
Mass evacuation with decompressive craniotomy is considered a standard intervention for
acute subdural hematoma (ASDH). However, hemispheric swelling complicates the …

Dl-3-n-butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance

K Song, X Zeng, X Xie, R Zhu, J Liang… - Stroke and Vascular …, 2022 - svn.bmj.com
Background Cerebral venous disorder may have a harmful effect on ischaemic stroke;
however, the underlying mechanism remains to be elucidated. Although Dl-3-n …

Prophylactic effect and mechanism of p-coumaric acid against hypoxic cerebral edema in mice

Y Li, J Han, Y Zhang, Y Chen, Y Zhang - Respiratory physiology & …, 2019 - Elsevier
Our previous study found that the anti-hypoxia effect of Tibetan turnip (Brassica rapa ssp.
rapa) is directly related to its p-Coumaric acid (CA) and glucoside (pCoumaric acid-beta-d …

Findings of cognitive impairment at high altitude: relationships to acetazolamide use and acute mountain sickness

L Phillips, B Basnyat, Y Chang… - … Altitude Medicine & …, 2017 - liebertpub.com
Abstract Phillips, Lara, Buddha Basnyat, Yuchiao Chang, Erik R. Swenson, and N. Stuart
Harris. Findings of cognitive impairment at high altitude: relationships to acetazolamide use …

High-altitude illness in the pediatric population: a review of the literature on prevention and treatment

V Garlick, A O'Connor, CD Shubkin - Current Opinion in Pediatrics, 2017 - journals.lww.com
Increasing numbers of children are visiting high altitude destinations. Whereas most of these
child travelers will only experience mild to moderate symptoms of HAI, a small percentage …

Insufficient cerebral venous drainage predicts early edema in acute intracerebral hemorrhage

L Chen, M Xu, S Yan, Z Luo, L Tong, M Lou - Neurology, 2019 - AAN Enterprises
Objectives To explore the relationship between insufficient ipsilateral cerebral venous
drainage and the development of perihematomal edema (PHE) and functional outcome in …

Possible role of glymphatic system of the brain in the pathogenesis of high-altitude cerebral edema

M Simka, P Latacz, J Czaja - High Altitude Medicine & Biology, 2018 - liebertpub.com
In this article, we suggest that the glymphatic system of the brain can play an important role
in the pathogenesis of high-altitude cerebral edema (HACE). Water enters the intercellular …