[HTML][HTML] Resolving the paradox of colon cancer through the integration of genetics, immunology, and the microbiota
M Fidelle, S Yonekura, M Picard, A Cogdill… - Frontiers in …, 2020 - frontiersin.org
While colorectal cancers (CRC) are paradigmatic tumors invaded by effector memory
lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to …
lymphocytes, the mechanisms accounting for the relative resistance of MSI negative CRC to …
Prediction of the response of colorectal cancer to systemic therapy
JW Adlard, SD Richman, MT Seymour… - The lancet oncology, 2002 - thelancet.com
Adjuvant chemotherapy with fluorouracil and folinic acid improves overall survival for
resected carcinoma of the colon of Dukes' stage C by 10–12%. In metastatic disease …
resected carcinoma of the colon of Dukes' stage C by 10–12%. In metastatic disease …
DNA strand breaks and apoptosis induced by oxaliplatin in cancer cells
S Faivre, D Chan, R Salinas, B Woynarowska… - Biochemical …, 2003 - Elsevier
Platinum anticancer drugs, such as cisplatin, are thought to exert their activity by DNA
damage. Oxaliplatin, a clinically active diaminocyclohexane platinum compound, however …
damage. Oxaliplatin, a clinically active diaminocyclohexane platinum compound, however …
[HTML][HTML] Co-Delivery of Ylang Ylang Oil of Cananga odorata and Oxaliplatin Using Intelligent pH-Sensitive Lipid-Based Nanovesicles for the Effective Treatment of …
Smart pH-responsive niosomes loaded with either Oxaliplatin (Ox), Ylang ylang essential oil
(Y-oil), or co-loaded with both compounds (Ox-Y)(Ox@ NSs, Y@ NSs, and Ox-Y@ NSs …
(Y-oil), or co-loaded with both compounds (Ox-Y)(Ox@ NSs, Y@ NSs, and Ox-Y@ NSs …
Gene expression signature in advanced colorectal cancer patients select drugs and response for the use of leucovorin, fluorouracil, and irinotecan
M Del Rio, F Molina, C Bascoul-Mollevi… - Journal of Clinical …, 2007 - ascopubs.org
Purpose In patients with advanced colorectal cancer, leucovorin, fluorouracil, and irinotecan
(FOLFIRI) is considered as one of the reference first-line treatments. However, only about …
(FOLFIRI) is considered as one of the reference first-line treatments. However, only about …
Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based …
V Cohen, V Panet-Raymond, N Sabbaghian, I Morin… - Clinical cancer …, 2003 - AACR
Abstract Purpose: Fluorouracil (5-FU) is widely used in the treatment of colorectal cancer.
Methylenetetrahydrofolate reductase (MTHFR) could play an important role in the action of 5 …
Methylenetetrahydrofolate reductase (MTHFR) could play an important role in the action of 5 …
Improved anti-colorectal carcinomatosis effect of tannic acid co-loaded with oxaliplatin in nanoparticles encapsulated in thermosensitive hydrogel
Y Ren, X Li, B Han, N Zhao, M Mu, C Wang… - European Journal of …, 2019 - Elsevier
Tannic acid, a hydrolysable tannin, exists commonly in food plants. Tannic acid has already
been shown various anticancer mechanisms such as inhibiting the proliferation, inducing a …
been shown various anticancer mechanisms such as inhibiting the proliferation, inducing a …
Prognostic value of tumoral thymidylate synthase and p53 in metastatic colorectal cancer patients receiving fluorouracil-based chemotherapy: phenotypic and …
MC Etienne, M Chazal, P Laurent-Puig… - Journal of clinical …, 2002 - ascopubs.org
PURPOSE: The aim of this multicenter prospective study was to evaluate the role of
intratumoral parameters related to fluorouracil (FU) sensitivity in 103 metastatic colorectal …
intratumoral parameters related to fluorouracil (FU) sensitivity in 103 metastatic colorectal …
Oxaliplatin: a review of its use in combination therapy for advanced metastatic colorectal cancer
D Simpson, C Dunn, M Curran, KL Goa - Drugs, 2003 - Springer
Oxaliplatin (Eloxatin™) is the only platinum compound to show clinical activity in colorectal
cancer. The efficacy of a combination of oxaliplatin with various schedules of fluorouracil (5 …
cancer. The efficacy of a combination of oxaliplatin with various schedules of fluorouracil (5 …
[HTML][HTML] High-accuracy prediction of colorectal cancer chemotherapy efficacy using machine learning applied to gene expression data
S Amniouel, MS Jafri - Frontiers in Physiology, 2024 - frontiersin.org
Introduction: FOLFOX and FOLFIRI chemotherapy are considered standard first-line
treatment options for colorectal cancer (CRC). However, the criteria for selecting the …
treatment options for colorectal cancer (CRC). However, the criteria for selecting the …