Mitochondrial dysfunction in diabetic kidney disease

JM Forbes, DR Thorburn - Nature Reviews Nephrology, 2018 - nature.com
Globally, diabetes is the leading cause of chronic kidney disease and end-stage renal
disease, which are major risk factors for cardiovascular disease and death. Despite this …

Mechanisms of diabetic complications

JM Forbes, ME Cooper - Physiological reviews, 2013 - journals.physiology.org
It is increasingly apparent that not only is a cure for the current worldwide diabetes epidemic
required, but also for its major complications, affecting both small and large blood vessels …

Empagliflozin in heart failure: diuretic and cardiorenal effects

M Griffin, VS Rao, J Ivey-Miranda, J Fleming… - Circulation, 2020 - Am Heart Assoc
Background: Sodium-glucose cotransporter-2 inhibitors improve heart failure–related
outcomes. The mechanisms underlying these benefits are not well understood, but diuretic …

[图书][B] Guideline: Sodium intake for adults and children

World Health Organization - 2012 - apps.who.int
1 This publication is a World Health Organization (WHO) guideline. A WHO guideline is any
document, whatever its title, containing WHO recommendations about health interventions …

Nutrimetabolomics: an integrative action for metabolomic analyses in human nutritional studies

MM Ulaszewska, CH Weinert… - Molecular nutrition & …, 2019 - Wiley Online Library
The life sciences are currently being transformed by an unprecedented wave of
developments in molecular analysis, which include important advances in instrumental …

Water, hydration, and health

BM Popkin, KE D'Anci, IH Rosenberg - Nutrition reviews, 2010 - academic.oup.com
This review examines the current knowledge of water intake as it pertains to human health,
including overall patterns of intake and some factors linked with intake, the complex …

Prevalence, awareness, treatment and control of hypertension and salt intake in Portugal: changes over a decade. The PHYSA study

J Polonia, L Martins, F Pinto, J Nazare - Journal of hypertension, 2014 - journals.lww.com
Objective: To determine prevalence, awareness, treatment and control of hypertension and
the 24-h sodium excretion (24h-UNa) in the Portuguese adult population and to examine …

Role of the kidney in normal glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications

JE Gerich - Diabetic Medicine, 2010 - Wiley Online Library
Diabet. Med. 27, 136–142 (2010) Abstract Considerable data have accumulated over the
past 20 years, indicating that the human kidney is involved in the regulation of glucose via …

Neural control of renal function

GF Dibona, UC Kopp - Physiological reviews, 1997 - journals.physiology.org
The renal nerves are the communication link between the central nervous system and the
kidney. In response to multiple peripheral and central inputs, efferent renal sympathetic …

Mortality after hospitalization with mild, moderate, and severe hyponatremia

SS Waikar, DB Mount, GC Curhan - The American journal of medicine, 2009 - Elsevier
BACKGROUND: Hyponatremia is the most common electrolyte abnormality in hospitalized
individuals. METHODS: To investigate the association between serum sodium concentration …