Epilepsy is one of the most common and disabling chronic neurological disorders.
Antiseizure medications (ASMs), previously referred to as anticonvulsant or antiepileptic …

Abstract γ-Aminobutyric acid (GABA) is the most prevalent inhibitory neurotransmitter in the
mammalian brain and has been found to play an important role in the pathogenesis or the …

Tetraspanins (Tspans) are a family of four-span transmembrane proteins, known as plasma
membrane “master organizers.” They form Tspan-enriched microdomains (TEMs or TERMs) …

Neonatal seizures are the most prevalent and distinctive sign of neurologic dysfunction in
early life and pose an immense challenge for clinicians. Improvements in neonatal care …

Neonatal seizures constitute the most frequent presenting neurologic sign encountered in
the neonatal intensive care unit. Despite limited efficacy and safety data, phenobarbital …

Objective Neonatal seizures are the most frequent type of neurological emergency in
newborn infants, often being a consequence of prolonged perinatal asphyxia. Phenobarbital …

Acute symptomatic seizures caused by either diffuse or focal perinatal hypoxic–ischemic
insults and intracranial hemorrhage in term newborns make up the large majority of all …

Neonatal seizures are the most common neurological event in newborns, showing higher
prevalence in preterm than in full-term infants. In the majority of cases they represent acute …

Perinatal brain injury or neonatal encephalopathy (NE) is a state of disturbed neurological
function in neonates, caused by a number of different aetiologies. The most prominent cause …

Therapeutic drug monitoring (TDM) should be adopted in all neonatal intensive care units
(NICUs), where the most preterm and fragile babies are hospitalized and treated with many …