Epithelial to mesenchymal transition (EMT) occurs during the pathological process
associated with tumor progression and is considered to influence and promote the …

The increase in recent scientific studies on cancer biomarkers has brought great new
insights into the field. Moreover, novel technological breakthroughs such as long read …

Circulating cell-free DNA (cfDNA) isolated from blood has been identified as a potential
biomarker in numerous fields, and has been the object of intensive research over the past …

Liquid biopsy, a minimally invasive approach, is a highly powerful clinical tool for the real‐
time follow‐up of cancer and overcomes many limitations of tissue biopsies. Epigenetic …

To clarify the mechanisms of diseases, such as cancer, studies analyzing genetic mutations
have been actively conducted for a long time, and a large number of achievements have …

Cell-free circulating DNA (cfDNA) in plasma has gained global interest as a diagnostic
material for noninvasive prenatal testing and cancer diagnosis, or the so-called “liquid …

Background Hepatocellular carcinoma (HCC) is the one of the most common cancers and
lethal diseases in the world. DNA methylation alteration is frequently observed in HCC and …

Robust and clinically convenient biomarkers for cancer diagnosis, early detection, and
prognosis have great potential to improve patient survival and are the key to precision …

Irritable bowel syndrome (IBS) is a brain-gut axis disorder characterized by abdominal pain
and altered bowel habits. IBS is a multifactorial, stress-sensitive disorder with evidence for …

Simple Summary Signal transducer and activator of transcription 3 (STAT3)/Cyclin-
dependent kinases are multifunctional proteins that play instrumental roles in …