Background: In many respects Archaea are much more like eukaryotes than prokaryotes
with respect to the conservation of many of the components involved in transcription …

Mitomycin C (MMC) is a genotoxic agent that induces DNA cross-links, DNA alkylation, and
the production of reactive oxygen species (ROS). MMC induces the SOS response and …

Aim: Nonthermal atmospheric‐pressure plasmas offer significant advantages as an
emerging disinfection approach. However the mechanisms of inactivation, and thus the …

Airborne particulate matter, PM10 and PM2. 5, are associated with a range of health effects
including lung cancer. Their complex organic fraction contains genotoxic and carcinogenic …

We cloned two genes encoding DNA polymerases from the hyperthermophilic archaeon
Pyrodictium occultum. The deduced primary structures of the two gene products have …

During the past two decades, the comet-based in vitro DNA repair assay has been used
regularly to measure base excision repair (BER)-related DNA incision activity. Most studies …

To identify the branch migration activity in archaea, we fractionated Pyrococcus furiosus cell
extracts by several chromatography and assayed for ATP-dependent resolution of synthetic …

Expression of mutant EcoRII methyltransferase protein (M. EcoRII-C186A) in Escherichia
coli leads to tightly bound DNA-protein complexes (TBCs), located sporadically on the …

MATERIALS AND METHODS Bacterial Strains-B. caldotenax strain YT-G, DSM406, was
obtained from Deutsche Sammlung von Mikroorganis men. The strain was grown at 65• Ž …

抄録 We identified a DNA polymerase with properties that differed from those of α-like DNA
polymerase (Pol I), in Pyrococcus furiosus, a hyperthermophilic archaeon. The novel DNA …