[HTML][HTML] Oxidized C5-methyl cytosine bases in DNA: 5-Hydroxymethylcytosine; 5-formylcytosine; and 5-carboxycytosine
A Klungland, AB Robertson - Free Radical Biology and Medicine, 2017 - Elsevier
Recent reports suggest that the Tet enzyme family catalytically oxidize 5-methylcytosine in
mammalian cells. The oxidation of 5-methylcytosine can result in three chemically distinct …
mammalian cells. The oxidation of 5-methylcytosine can result in three chemically distinct …
Diet and aging
S Ribarič - Oxidative medicine and cellular longevity, 2012 - Wiley Online Library
Nutrition has important long‐term consequences for health that are not only limited to the
individual but can be passed on to the next generation. It can contribute to the development …
individual but can be passed on to the next generation. It can contribute to the development …
Genome-wide sperm DNA methylation changes after 3 months of exercise training in humans
Aim: DNA methylation programs gene expression and is involved in numerous biological
processes. Accumulating evidence supports transgenerational inheritance of DNA …
processes. Accumulating evidence supports transgenerational inheritance of DNA …
Alzheimer's disease and epigenetic diet
Z Sezgin, Y Dincer - Neurochemistry international, 2014 - Elsevier
Alzheimer's disease (AD) is the most common neurodegenerative disease. Many efforts
have been directed to prevent AD due to its rising prevalence and the lack of an effective …
have been directed to prevent AD due to its rising prevalence and the lack of an effective …
Cangfu Daotan Wan alleviates polycystic ovary syndrome with phlegm-dampness syndrome via disruption of the PKP3/ERCC1/MAPK axis
Y Li, H Wu, Y Guo, C Wei, L Guan, W Ju… - Journal of Ovarian …, 2023 - Springer
Abstract Background/Aim Cangfu Daotan Wan (CFDTW) has been widely used for polycystic
ovary syndrome (PCOS) patients in the type of stagnation of phlegm and dampness. In this …
ovary syndrome (PCOS) patients in the type of stagnation of phlegm and dampness. In this …
Laboratory methods to decipher epigenetic signatures: a comparative review
R Halabian, V Arshad, A Ahmadi, P Saeedi… - Cellular & Molecular …, 2021 - Springer
Epigenetics refers to nucleotide sequence-independent events, and heritable changes,
including DNA methylation and histone modification (as the two main processes) …
including DNA methylation and histone modification (as the two main processes) …
Multilocus loss of DNA methylation in individuals with mutations in the histone H3 lysine 4 demethylase KDM5C
D Grafodatskaya, BHY Chung, DT Butcher… - BMC Medical …, 2013 - Springer
Background A number of neurodevelopmental syndromes are caused by mutations in genes
encoding proteins that normally function in epigenetic regulation. Identification of epigenetic …
encoding proteins that normally function in epigenetic regulation. Identification of epigenetic …
[HTML][HTML] Alzheimer's disease is an inherent, natural part of human brain aging: An integrated perspective
I Ferrer - Free Neuropathology, 2022 - ncbi.nlm.nih.gov
Alzheimer disease is one of the most challenging demons in our society due to its very high
prevalence and its clinical manifestations which cause deterioration of cognition …
prevalence and its clinical manifestations which cause deterioration of cognition …
Role of DNA methylation in bisphenol A exposed mouse spermatocyte
L Yin, Y Dai, X Jiang, Y Liu, H Chen, F Han… - Environmental …, 2016 - Elsevier
As a widespread environmental contaminant, bisphenol A (2, 2-bis (4-hydroxyphenyl)
propane, BPA) has been implicated in male reproductive function injury. Previous studies …
propane, BPA) has been implicated in male reproductive function injury. Previous studies …
Antioxidant diets and functional foods promote healthy aging and longevity through diverse mechanisms of action
S Wichansawakun, HS Buttar - The role of functional food security in global …, 2019 - Elsevier
It is well recognized that humans are enjoying longer life spans than their ancestors.
However, longevity has resulted in a larger geriatric population worldwide, posing an …
However, longevity has resulted in a larger geriatric population worldwide, posing an …