Medical treatment for small abdominal aortic aneurysms

G Rughani, L Robertson… - Cochrane database of …, 2012 - cochranelibrary.com
Background Screening for abdominal aortic aneurysm (AAA) in selected groups is now
performed in England, the USA and Sweden. Patients with aneurysms over 55 mm in …

Inflammaging and proteases in abdominal aortic aneurysm

A Hendel, LS Ang, DJ Granville - Current vascular …, 2015 - ingentaconnect.com
Abdominal aortic aneurysm (AAA) is an age-related disease resulting in aortic wall
weakening and dilatation which may progress to the fatal point of abrupt aortic wall rupture …

Multifunctional nanoparticles for doxycycline delivery towards localized elastic matrix stabilization and regenerative repair

B Sivaraman, A Ramamurthi - Acta biomaterialia, 2013 - Elsevier
Abdominal aortic aneurysms (AAAs) are abnormal expansions of the aortic wall, typically
characterized by chronic up-regulation of matrix metalloproteases (MMPs)-2 and-9. These …

In vivo quantification of murine aortic cyclic strain, motion, and curvature: implications for abdominal aortic aneurysm growth

CJ Goergen, KN Barr, DT Huynh… - Journal of Magnetic …, 2010 - Wiley Online Library
Purpose To develop methods to quantify cyclic strain, motion, and curvature of the murine
abdominal aorta in vivo. Materials and Methods C57BL/6J and apoE−/− mice underwent …

Magnetically-responsive, multifunctional drug delivery nanoparticles for elastic matrix regenerative repair

B Sivaraman, G Swaminathan, L Moore, J Fox… - Acta Biomaterialia, 2017 - Elsevier
Arresting or regressing growth of abdominal aortic aneurysms (AAAs), localized expansions
of the abdominal aorta are contingent on inhibiting chronically overexpressed matrix …

Inhibitory effects of doxycycline on the onset and progression of abdominal aortic aneurysm and its related mechanisms

M Yu, C Chen, Y Cao, R Qi - European journal of pharmacology, 2017 - Elsevier
The objective of this study was to investigate whether doxycycline (DOX) given at different
doses and via different administration routes had protective or therapeutic effects on …

Mechanisms underlying the inhibitory effects of probucol on elastase‐induced abdominal aortic aneurysm in mice

C Chen, Y Wang, Y Cao, Q Wang… - British Journal of …, 2020 - Wiley Online Library
Background and Purpose Abdominal aortic aneurysm (AAA) is a degenerative disease with
irreversible and progressive dilation of the artery. But there are few options for efficacious …

Influence of statin therapy on aneurysm sac regression after endovascular aortic repair

W Kim, RT Gandhi, CS Peña, RE Herrera… - Journal of Vascular and …, 2017 - Elsevier
Purpose To determine whether statin therapy is associated with abdominal aortic aneurysm
(AAA) sac regression after endovascular aneurysm repair (EVAR). Materials and Methods A …

Abdominal aortic aneurysm: An often asymptomatic and fatal men's health issue

K Tillman, OD Lee, K Whitty - American Journal of Men's …, 2013 - journals.sagepub.com
Men are more likely than women to develop an abdominal aortic aneurysm (AAA), a disease
that is often asymptomatic and has up to a 90% risk of mortality if the aneurysm ruptures …

Comparison of efficacy between ramipril and carvedilol on limiting the expansion of abdominal aortic aneurysm in mouse model

SM Park, MK Hong, SH Kim, S Jung… - Journal of …, 2019 - journals.sagepub.com
Objective: Abdominal aortic aneurysm (AAA) is a common condition that may be life-
threatening when it is unrecognized. The aim of this study is to evaluate and compare the …