Prenatal alcohol exposure: profiling developmental DNA methylation patterns in central and peripheral tissues
Background: Prenatal alcohol exposure (PAE) can alter the development of neurobiological
systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits …
systems, leading to lasting neuroendocrine, neuroimmune, and neurobehavioral deficits …
Statistical approaches for the analysis of DNA methylation microarray data
KD Siegmund - Human genetics, 2011 - Springer
Following the rapid development and adoption in DNA methylation microarray assays, we
are now experiencing a growth in the number of statistical tools to analyze the resulting …
are now experiencing a growth in the number of statistical tools to analyze the resulting …
DNA methylation: an epigenetic risk factor in preterm birth
Spontaneous preterm birth (PTB; birth prior to 37 weeks of gestation) is a complex
phenotype with multiple risk factors that complicate our understanding of its etiology. A …
phenotype with multiple risk factors that complicate our understanding of its etiology. A …
Epigenetic therapies in MDS and AML
EA Griffiths, SD Gore - Epigenetic Alterations in Oncogenesis, 2012 - Springer
The use of low dose hypomethylating agents for patients with myelodysplastic syndrome
(MDS) and secondary acute myeloid leukemia (AML) has had made a significant impact. In …
(MDS) and secondary acute myeloid leukemia (AML) has had made a significant impact. In …
[图书][B] Evo-devo of child growth: treatise on child growth and human evolution
Z Hochberg - 2011 - books.google.com
Working with principles from the fields of evolutionary and developmental biology (evo-
devo), this fascinating work offers a new approach to analyzing child growth and …
devo), this fascinating work offers a new approach to analyzing child growth and …
Accurate genome-scale percentage DNA methylation estimates from microarray data
DNA methylation is a key regulator of gene function in a multitude of both normal and
abnormal biological processes, but tools to elucidate its roles on a genome-wide scale are …
abnormal biological processes, but tools to elucidate its roles on a genome-wide scale are …
Genome-wide DNA methylation profiling of non-small cell lung carcinomas
Background Non-small cell lung carcinoma (NSCLC) is a complex malignancy that owing to
its heterogeneity and poor prognosis poses many challenges to diagnosis, prognosis and …
its heterogeneity and poor prognosis poses many challenges to diagnosis, prognosis and …
Genome-wide epigenetic modifications in cancer
Epigenetic alterations in cancer include changes in DNA methylation and associated
histone modifications that influence the chromatin states and impact gene expression …
histone modifications that influence the chromatin states and impact gene expression …
Low-dose Cd induces hepatic gene hypermethylation, along with the persistent reduction of cell death and increase of cell proliferation in rats and mice
B Wang, Y Li, Y Tan, X Miao, XD Liu, C Shao… - PLoS …, 2012 - journals.plos.org
Background Cadmium (Cd) is classified as a human carcinogen probably associated with
epigenetic changes. DNA methylation is one of epigenetic mechanisms by which cells …
epigenetic changes. DNA methylation is one of epigenetic mechanisms by which cells …
Cigarette smoke-induced hypermethylation of the GCLC gene is associated with COPD
L Cheng, J Liu, B Li, S Liu, X Li, H Tu - Chest, 2016 - Elsevier
Background Cigarette smoking is a major environmental contributor to COPD, but
understanding its epigenetic regulation of oxidative genes involved in the pathogenesis of …
understanding its epigenetic regulation of oxidative genes involved in the pathogenesis of …