MicroRNAs (miRNAs) are a group of small non-coding RNAs that post-transcriptionally
control expression of genes by targeting mRNAs. miRNA alterations partake in the …

As a milestone in therapeutic fields, tissue engineering has offered an alternative strategy to
address unmet clinical needs for the repair and replacement of human damaged organs …

Exosomes participate in intercellular communication and glioma microenvironment
modulation, but the exact mechanisms by which glioma-derived exosomes (GDEs) promote …

Breast cancer is the most prevalent cancer in the world. Currently, the main treatments for
breast cancer are radiotherapy, chemotherapy, targeted therapy and surgery. The treatment …

The global burden of breast cancer (BC) is increasing significantly. This trend is caused by
several factors such as late diagnosis, limited treatment options for certain BC subtypes …

Bone remodeling is a continuous and dynamic process of bone formation and resorption to
maintain its integrity and homeostasis. Bone marrow is a source of various cell lineages …

miRNAs are some of the most well-characterized regulators of gene expression. Integral to
several physiological processes, their aberrant expression often drives the pathogenesis of …

Epigenetics is the study of heritable molecular determinants that are independent of
phenotypic features. The epigenetic features include DNA methylation, histone …

Exosomes are endosome-derived microvesicles that carry cell-specific biological cargo,
such as proteins, lipids, and noncoding RNAs (ncRNAs). They play a key role in bone …

Breast cancer, a multifactorial disease, represents one of the leading causes of cancer-
related morbidity and mortality in women. This study set out to elucidate the underlying …