DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Summary N 6-Methyldeoxyadenosine (6mA) has recently been shown to exist and play
regulatory roles in eukaryotic genomic DNA (gDNA). However, the biological functions of …

A deeper understanding of the pathomechanisms leading to stress-related psychiatric
disorders is important for the development of more efficient preventive and therapeutic …

The chemical modification of DNA bases plays a key role in epigenetic gene regulation.
While much attention has been focused on the classical epigenetic mark, 5-methylcytosine …

DNA methylation is one of the most extensively studied epigenetic marks. It is involved in
transcriptional gene silencing and plays important roles during mammalian development. Its …

DNA methylation is considered a stable epigenetic mark, yet methylation patterns can vary
during differentiation and in diseases such as cancer. Local levels of DNA methylation result …

Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Purpose: Ionizing radiation (IR) is a ubiquitous environmental stressor with genotoxic and
epigenotoxic capabilities. Terrestrial IR, predominantly a low-linear energy transfer (LET) …

The past decade has witnessed a number of societal and political changes that have raised
critical questions about the long-term impact of marijuana (Cannabis sativa) that are …