We have reviewed the literature and have identified more than 100 diseases or conditions
that are associated with raised concentrations of plasma total homocysteine. The …

DNA methylation is an epigenetic mechanism that is essential for regulating gene
transcription. However, aberrant DNA methylation, which is a nearly universal finding in …

Metabolites, including those generated during ethanol metabolism, can impact disease
states by binding to transcription factors and/or modifying chromatin structure, thereby …

The incidence of esophageal adenocarcinoma (EAC) has increased in recent decades, and
its 5-year survival rate is less than 20%. As a well-established precursor, patients with …

Micronutrients are essential components of the diet and are required to maintain
fundamental bodily functions. Liver disease has a profound effect on nutrient intake …

Objectives To examine the strengths and limitations of existing data to provide guidance for
the use of folate supplements as treatment, with or without other psychotropic medications …

El alcohol afecta al cerebro ya la mayoría de los órganos y sistemas y se relaciona con
numerosos problemas sanitarios, incluyendo enfermedades mentales, neurológicas …

Ample evidence indicates that ethanol-induced oxidative stress and mitochondrial
dysfunction are central to the pathogenesis of alcoholic liver disease (ALD). As an adaptive …

Neurodegeneration represents a global problem due to the progressive increase in the
aging population all over the world. The quality of life in aging and the cost for the health …

Malnutrition encompassing both macro-and micro-nutrient deficiency, remains one of the
most frequent complications of alcohol-related liver disease (ArLD). Protein-energy …