Despite much progress in regulations to improve paediatric drug development, there
remains a significant need to develop better medications for children. For the design of oral …

The review examined whether premedication with oral midazolam in children undergoing
general anaesthesia improved behavioural outcomes. It concluded that 0.5 mg/kg oral …

Background: We undertook a study to determine the effects of four routes of administation on
the efficacy of midazolam for premedication. Methods: In a randomized double‐blind study …

Covering everything from preoperative evaluation to neonatal emergencies to the PACU, A
Practice of Anesthesia in Infants and Children, 6th Edition, features state-of-the-art advice on …

Children undergo a preoperative fast in an at-tempt to minimize the fluid and solid food
component of gastric contents. The importance of a preoperative fast was acknowledged …

Background: Pre‐anesthetic anxiety and emergence agitation are major challenges for
anesthesiologists in pediatric anesthesia. Thus, sedative premedication and parental …

Background Sevoflurane is a volatile anesthetic agent with low pungency, non-irritating
odor, and low blood/gas partition coefficient that makes it an attractive alternative to …

Results Median parental separation (3 vs. 2; P= 0.01), induction quality (2 vs. 2; P= 0.03)
and sedation scores (3 vs. 2; P= 0.003) were significantly better in the MH group compared …

A randomised, controlled, crossover trial was designed to assess the safety and
effectiveness of oral midazolam sedation for orthodontic extractions. Forty‐six ASA physical …

Objective Current practice guidelines do not recommend benzodiazepines for acute
management of anxiety disorders in pediatric patients. However, in procedural settings …