[HTML][HTML] The Vaginal Microenvironment: The Physiologic Role of Lactobacilli

E Amabebe, DOC Anumba - Frontiers in medicine, 2018 - frontiersin.org
In addition to being a passage for sperm, menstruum, and the baby, the human vagina and
its microbiota can influence conception, pregnancy, the mode and timing of delivery, and the …

Mechanistic differences leading to infectious and sterile inflammation

F Behnia, S Sheller, R Menon - American journal of …, 2016 - Wiley Online Library
Inflammation is a physiologic component of pregnancy and parturition. Overwhelming
intrauterine inflammatory load promotes quiescent feto‐maternal tissues into a contractile …

Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

AK Smith, V Kilaru, M Kocak, LM Almli, KB Mercer… - BMC genomics, 2014 - Springer
Background Individual genotypes at specific loci can result in different patterns of DNA
methylation. These methylation quantitative trait loci (meQTLs) influence methylation across …

[HTML][HTML] Parental preconception exposure to phenol and phthalate mixtures and the risk of preterm birth

Y Zhang, V Mustieles, PL Williams, BJ Wylie… - Environment …, 2021 - Elsevier
Background Parental preconception exposure to select phenols and phthalates was
previously associated with increased risk of preterm birth in single chemical analyses …

First Trimester Prediction of Preterm Birth in Patient Plasma with Machine-Learning-Guided Raman Spectroscopy and Metabolomics

L Synan, S Ghazvini, S Uthaman… - … Applied Materials & …, 2023 - ACS Publications
Preterm birth (PTB) is the leading cause of infant deaths globally. Current clinical measures
often fail to identify women who may deliver preterm. Therefore, accurate screening tools are …

[HTML][HTML] Maternal and paternal preconception exposure to phenols and preterm birth

V Mustieles, Y Zhang, J Yland, JM Braun… - Environment …, 2020 - Elsevier
Background Phenol exposure during pregnancy has been associated with preterm birth, but
the potential effect of preconception exposure in either parent is unknown. There is a …

[HTML][HTML] Early-and late-onset preeclampsia and the tissue-specific epigenome of the placenta and newborn

EM Herzog, AJ Eggink, SP Willemsen, RC Slieker… - Placenta, 2017 - Elsevier
Introduction Preeclampsia (PE) carries increased risks of cardiovascular-and metabolic
diseases in mothers and offspring during the life course. While the severe early-onset PE …

Association of parental preconception exposure to phthalates and phthalate substitutes with preterm birth

Y Zhang, V Mustieles, J Yland, JM Braun… - JAMA network …, 2020 - jamanetwork.com
Importance Although phthalate exposure during pregnancy has been associated with
preterm birth, the association of preconception exposure in either parent with preterm birth …

Fetal DNA methylation associates with early spontaneous preterm birth and gestational age

SE Parets, KN Conneely, V Kilaru, SJ Fortunato… - PloS one, 2013 - journals.plos.org
Spontaneous preterm birth (PTB,< 37 weeks gestation) is a major public health concern, and
children born preterm have a higher risk of morbidity and mortality throughout their lives …

Methods for mediation analysis with high-dimensional DNA methylation data: Possible choices and comparisons

D Clark-Boucher, X Zhou, J Du, Y Liu… - PLoS …, 2023 - journals.plos.org
Epigenetic researchers often evaluate DNA methylation as a potential mediator of the effect
of social/environmental exposures on a health outcome. Modern statistical methods for …