Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in
sight. Complications of DM2 involve a myriad of comorbidities including the serious …

Angiogenesis is involved in physiological and pathological processes in the body. Tumor
angiogenesis is a key factor associated with tumor growth, progression, and metastasis …

An in vivo model of antiangiogenic therapy allowed us to identify genes upregulated by
bevacizumab treatment, including Fatty Acid Binding Protein 3 (FABP3) and FABP7, both of …

Hypoxia-inducible factor 1 alpha (HIF-1α) orchestrates cellular adaptation to low oxygen and
nutrient-deprived environment and drives progression to malignancy in human solid …

Significance: Poor wound healing remains a significant health issue for a large number of
patients in the United States. The physiologic response to local wound hypoxia plays a …

Infantile haemangiomas (IH) are the most common benign tumours of infancy. Although
most IH are innocuous and 85–90% regress spontaneously, some may become life‐or …

Hypoxia-inducible factors (HIFs) are essential mediators of the cellular oxygen-signaling
pathway. They are heterodimeric transcription factors consisting of an oxygen-sensitive …

Angiogenesis is the process of blood vessel growth. The angiogenic switch consists of new
blood vessel formation that, in carcinogenesis, can lead to the transition from a harmless …

A plant kingdom is considered as a gold mine for the discovery of many biologically active
substances with therapeutic values. Resveratrol (3, 5, 4′-trihydroxystilbene), a naturally …

Hypoxia-inducible factor (HIF) is a main heterodimeric transcription factor that regulates the
cellular adaptive response to hypoxia by stimulating the transcription of a series of hypoxia …