Colorectal cancer remains a major public health problem worldwide. Despite the
introduction of antiangiogenic drugs for the treatment of metastatic disease, a large number …

Tibial dyschondroplasia (TD) is a skeletal abnormality that can cause economic losses and
animal welfare concerns. Thiram-induced TD is characterized by enlarged, unvascularized …

Loss of the von Hippel-Lindau (VHL) tumor suppressor gene contributes to proliferative
disorders including renal cell carcinoma. The consequence of VHL loss is increased levels …

Endosialin is a transmembrane glycoprotein selectively expressed in blood vessels and
stromal fibroblasts of various human tumours. It has been functionally implicated in …

Murine hindlimb ischemia is a useful model for investigation of the mechanisms of
peripheral arterial disease and for understanding the role of endothelial cells and generic …

It was hypothesized that mobilization vs immobilization after injury would promote tissue
healing by regulating gene expression for molecules associated with repair. Cast …

Hypoxia is a consequence of inadequate oxygen availability. At the cellular level, lowered
oxygen concentration activates signal cascades including numerous receptors, ion …

Diabetic foot ulcer (DFU) is a complication from incomplete or prolonged wound healing, at
times requires amputation, putting substantial health and socioeconomic burden. Wound …

Abstract Background and Aim Aryl‐hydrocarbon receptor nuclear translocator 2 (ARNT2) is
a transcriptional regulator and member of the basic helix‐loop‐helix/P er‐ARNT‐SIM …

A thorough understanding of vascular biology will assist the reconstructive surgeon in both
operative planning and development of novel surgical approaches to treat chronic wounds …