Interferons (IFNs) are soluble glycoproteins secreted by infected and transformed cells.
Since their discovery in 1957 as a factor that “interferes” with viral replication, IFNs have …

The expression of genes is altered in various diseases and is responsible for the disease's
initiation, progression and pathology. Several other genes, predominantly inactivated, may …

抄録 Introduction: Whether good baseline quality of life (QOL) is linked to improved QOL:
improved overall survival (OS) which is relevant to HLA-restricted peptides has not been …

HML6-c14, a long terminal repeat (LTR)-type retrotransposon identified by expressed
sequence tag (EST) database screening, was found to undergo RNA processing resembling …

抄録 Introduction: Whether human leukocyte antigens (HLAs) and human endogenous
retroviruses (HERVs) affect therapeutic outcomes is unknown. Here, we focused on the …

抄録 Introduction: Some patients are more susceptible to multiple primary malignancies
(MPMs). However, understanding of the effects of this susceptibility on the benefits and …

Objective: To improve the understanding of the etiology of perforated peptic ulcers (PPUs)
and their association with cancer development. Design: Patients with (n= 303) and without …

Abstract T-cell receptor (TCR)-and chimeric antigen receptor (CAR)-based adoptive cell
transfer (ACT) has shown promising results in hematological malignancies, but remains …

Although the oncolytic parvovirus H-1PV has entered clinical trials, predicting therapeutic
success remains challenging. We investigated whether the antiviral state in tumor cells …

Human endogenous retroviruses (HERVs) are transcribed in many cancer types, including
head and neck cancer. Because of accumulating mutations at proviral loci over evolutionary …