Endoplasmic reticulum stress in elderly patients with COVID-19: potential of melatonin treatment
GT Yiang, CC Wu, CL Lu, WC Hu, YJ Tsai, YM Huang… - Viruses, 2023 - mdpi.com
Aging processes, including immunosenescence, inflammation, inflammasome formation,
genomic instability, telomeric attrition, and altered autophagy, are involved in viral infections …
genomic instability, telomeric attrition, and altered autophagy, are involved in viral infections …
Safety and efficacy of melatonin as an adjuvant therapy in COVID-19 patients: Systematic review and meta-analysis
AM Taha, SAA Saed, MHE Moawad… - Advances in medical …, 2023 - Elsevier
Background Melatonin might be beneficial to coronavirus disease 2019 (COVID-19) patients
in terms of both prevention and treatment. We investigated how melatonin affected various …
in terms of both prevention and treatment. We investigated how melatonin affected various …
Redox Homeostasis Alteration Is Restored through Melatonin Treatment in COVID-19 Patients: A Preliminary Study
ME Soto, I Pérez-Torres, L Manzano-Pech… - International Journal of …, 2024 - mdpi.com
Type II pneumocytes are the target of the SARS-CoV-2 virus, which alters their redox
homeostasis to increase reactive oxygen species (ROS). Melatonin (MT) has antioxidant …
homeostasis to increase reactive oxygen species (ROS). Melatonin (MT) has antioxidant …
Development of indolealkylamine derivatives as potential multi-target agents for COVID-19 treatment
COVID-19 is a complex disease with short-term and long-term respiratory, inflammatory and
neurological symptoms that are triggered by the infection with SARS-CoV-2. As many drugs …
neurological symptoms that are triggered by the infection with SARS-CoV-2. As many drugs …
Melatonin: a ferroptosis inhibitor with potential therapeutic efficacy for the post-COVID-19 trajectory of accelerated brain aging and neurodegeneration
A Yehia, OA Abulseoud - Molecular Neurodegeneration, 2024 - Springer
The unprecedented pandemic of COVID-19 swept millions of lives in a short period, yet its
menace continues among its survivors in the form of post-COVID syndrome. An …
menace continues among its survivors in the form of post-COVID syndrome. An …
The clinical efficacy of melatonin in the treatment of patients with COVID-19: a systematic review and meta-analysis of randomized controlled trials
Background The COVID-19 pandemic has resulted in significant morbidity and mortality
worldwide, with cytokine storm leading to exaggerating immune response, multi-organ …
worldwide, with cytokine storm leading to exaggerating immune response, multi-organ …
Role of Melatonin in Viral, Bacterial and Parasitic Infections
GJM Maestroni - Biomolecules, 2024 - mdpi.com
In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …
[HTML][HTML] The inhibitory and inactivating effects of visible light on SARS-CoV-2: A narrative update
S Gorman - Journal of Photochemistry and Photobiology, 2023 - Elsevier
Prior to the coronavirus disease-19 (COVID-19) pandemic, the germicidal effects of visible
light (λ= 400–700 nm) were well known. This review provides an overview of new findings …
light (λ= 400–700 nm) were well known. This review provides an overview of new findings …
Neglected Effective Early Therapies against COVID-19: Focus on Functional Foods and Related Active Substances. A Review
A Donzelli - 2023 - preprints.org
The official recommendations to manage COVID-19 in the outpatient setting focus on high-
cost drugs (remdesivir, nirmatrelvir-ritonavir, molnupiravir), suffering from many problems …
cost drugs (remdesivir, nirmatrelvir-ritonavir, molnupiravir), suffering from many problems …
Melatonin as adjuvant treatment in COVID-19 patients. A meta-analysis of randomized and propensity matched studies
Melatonin is a neurohormone well-known as sleep disorder treatment. A few clinical trials
have recently pointed out the biological plausibility of utilising melatonin in the treatment of …
have recently pointed out the biological plausibility of utilising melatonin in the treatment of …