[HTML][HTML] Epigenetics of male infertility: the role of DNA methylation
JC Rotondo, C Lanzillotti, C Mazziotta… - Frontiers in Cell and …, 2021 - frontiersin.org
In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …
Age-associated epigenetic changes in mammalian sperm: implications for offspring health and development
V Ashapkin, A Suvorov, JR Pilsner… - Human …, 2023 - academic.oup.com
BACKGROUND Modern reproductive behavior in most developed countries is characterized
by delayed parenthood. Older gametes are generally less fertile, accumulating and …
by delayed parenthood. Older gametes are generally less fertile, accumulating and …
Genetics of male infertility
C Krausz, V Rosta, RS Swerdloff, C Wang - Emery and rimoin's principles …, 2022 - Elsevier
Approximately 7% of men suffer from fertility problems, the etiology of which are ascribable
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …
to a number of factors acting at pretesticular, posttesticular, or testicular levels. About 20% of …
Consequences of paternal nutrition on offspring health and disease
P Dimofski, D Meyre, N Dreumont, B Leininger-Muller - Nutrients, 2021 - mdpi.com
It is well established that the maternal diet during the periconceptional period affects the
progeny's health. A growing body of evidence suggests that the paternal diet also influences …
progeny's health. A growing body of evidence suggests that the paternal diet also influences …
[HTML][HTML] Lifestyle interventions to reduce endocrine-disrupting phthalate and phenol exposures among reproductive age men and women: A review and future steps
Non-persistent endocrine-disrupting chemicals (EDCs), including phthalates and phenols,
are ubiquitous in both the environment and human body. A growing body of epidemiologic …
are ubiquitous in both the environment and human body. A growing body of epidemiologic …
Frequency, morbidity and equity—the case for increased research on male fertility
S Kimmins, RA Anderson, CLR Barratt… - Nature Reviews …, 2024 - nature.com
Currently, most men with infertility cannot be given an aetiology, which reflects a lack of
knowledge around gamete production and how it is affected by genetics and the …
knowledge around gamete production and how it is affected by genetics and the …
Impact of endocrine disruptors upon non-genetic inheritance
D Montjean, AS Neyroud, MG Yefimova… - International Journal of …, 2022 - mdpi.com
Similar to environmental factors, EDCs (endocrine-disrupting chemicals) can influence gene
expression without modifying the DNA sequence. It is commonly accepted that the …
expression without modifying the DNA sequence. It is commonly accepted that the …
Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records
Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …
spermatogenesis defects, male infertility and poor developmental outcomes have been …
Sperm epigenetic clock associates with pregnancy outcomes in the general population
JR Pilsner, H Saddiki, BW Whitcomb… - Human …, 2022 - academic.oup.com
STUDY QUESTION Is sperm epigenetic aging (SEA) associated with probability of
pregnancy among couples in the general population? SUMMARY ANSWER We observed a …
pregnancy among couples in the general population? SUMMARY ANSWER We observed a …
[HTML][HTML] Mixtures of per-and polyfluoroalkyl substances (PFAS) alter sperm methylation and long-term reprogramming of offspring liver and fat transcriptome
DAL Maxwell, OA Oluwayiose, E Houle, K Roth… - Environment …, 2024 - Elsevier
Male fertility has been declining worldwide especially in countries with high levels of
endocrine disrupting chemicals (EDCs). Per-and polyfluorinated alkyl Substances (PFAS) …
endocrine disrupting chemicals (EDCs). Per-and polyfluorinated alkyl Substances (PFAS) …