Background The efficacy of vaginal progesterone for preventing preterm birth and adverse
perinatal outcomes in singleton gestations with a short cervix has been questioned after …

The steroid hormones progestagens, estrogens, androgens, and glucocorticoids as well as
their precursor cholesterol are required for successful establishment and maintenance of …

Preeclampsia (PE) results in placental dysfunction and is one of the primary causes of
maternal and fetal mortality and morbidity. During pregnancy, estrogen is produced primarily …

Preterm birth is the most important cause of neonatal mortality and morbidity worldwide. In
this review, we review potential risk factors associated with preterm birth and the subsequent …

Background Preterm birth is a major complication of pregnancy associated with perinatal
mortality and morbidity. Progesterone for the prevention of preterm labour has been …

We have examined factors concerned with the maintenance of uterine quiescence during
pregnancy and the onset of uterine activity at term in an animal model, the sheep, and in …

The principal modulators of the hypothalamic‐pituitary‐adrenal (HPA) axis are corticotropin‐
releasing hormone (CRH) and arginine‐vasopressin (AVP). Corticotropin‐releasing …

Hormonal changes during pregnancy instigate numerous physiological changes aimed at
the growth and delivery of a healthy baby. A careful balance between immunological …

E. Functional development 1. Ontogeny of steroidogenic activity 2. Functional zonation and
ontogeny of steroidogenic enzyme expression 3. Responsiveness to ACTH III. Regulation A …

Continuous efforts have been devoted to unraveling the biophysiology and development of
the human fetal adrenal cortex, which is structurally and functionally unique from other …