In vitro and in vivo effects of IGF-1 delivery strategies on tendon healing: a review
I Miescher, J Rieber, M Calcagni… - International Journal of …, 2023 - mdpi.com
Tendon injuries suffer from a slow healing, often ending up in fibrovascular scar formation,
leading to inferior mechanical properties and even re-rupture upon resumption of daily work …
leading to inferior mechanical properties and even re-rupture upon resumption of daily work …
The spatial landscape of progression and immunoediting in primary melanoma at single-cell resolution
Cutaneous melanoma is a highly immunogenic malignancy that is surgically curable at early
stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high …
stages but life-threatening when metastatic. Here we integrate high-plex imaging, 3D high …
RNA binding proteins in senescence: a potential common linker for age-related diseases?
Aging represents the major risk factor for the onset and/or progression of various disorders
including neurodegenerative diseases, metabolic disorders, and bone-related defects. As …
including neurodegenerative diseases, metabolic disorders, and bone-related defects. As …
Single-cell sequencing reveals the landscape of the human brain metastatic microenvironment
Brain metastases is the most common intracranial tumor and account for approximately 20%
of all systematic cancer cases. It is a leading cause of death in advanced-stage cancer …
of all systematic cancer cases. It is a leading cause of death in advanced-stage cancer …
[HTML][HTML] Viscoelastic hydrogels for interrogating pancreatic cancer-stromal cell interactions
The tumor microenvironment (TME) is known to direct cancer cell growth, migration, invasion
into the matrix and distant tissues, and to confer drug resistance in cancer cells. While …
into the matrix and distant tissues, and to confer drug resistance in cancer cells. While …
Solid diet manipulates rumen epithelial microbiota and its interactions with host transcriptomic in young ruminants
J Chai, X Lv, Q Diao, H Usdrowski… - Environmental …, 2021 - Wiley Online Library
Solid diet supplementation in the early life stages of ruminants could improve rumen
microbiota and tissue development. However, most studies focus on bacteria in the rumen …
microbiota and tissue development. However, most studies focus on bacteria in the rumen …
SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP2
K Masuo, R Chen, A Yogo, A Sugiyama… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer has an extremely poor prognosis because of its resistance to
conventional therapies. Cancer stem cell (CSC)‐targeted therapy is considered a promising …
conventional therapies. Cancer stem cell (CSC)‐targeted therapy is considered a promising …
[HTML][HTML] Single-cell landscape reveals the epithelial cell-centric pro-inflammatory immune microenvironment in dry eye development
Z Liu, H Xie, L Li, D Jiang, Y Qian, X Zhu, M Dai, Y Li… - Mucosal …, 2024 - Elsevier
Dry eye disease (DED) is a prevalent chronic eye disease characterized by an aberrant
inflammatory response in ocular surface mucosa. The immunological alterations underlying …
inflammatory response in ocular surface mucosa. The immunological alterations underlying …
NCBP2 and TFRC are novel prognostic biomarkers in oral squamous cell carcinoma
There are few prognostic biomarkers and targeted therapeutics currently in use for the
clinical management of oral squamous cell carcinoma (OSCC) and patient outcomes remain …
clinical management of oral squamous cell carcinoma (OSCC) and patient outcomes remain …
Promoting prognostic model application: a review based on gliomas
Malignant neoplasms are characterized by poor therapeutic efficacy, high recurrence rate,
and extensive metastasis, leading to short survival. Previous methods for grouping …
and extensive metastasis, leading to short survival. Previous methods for grouping …