[HTML][HTML] Advantages of vitrification preservation in assisted reproduction and potential influences on imprinted genes

H Chen, L Zhang, L Meng, L Liang, C Zhang - Clinical Epigenetics, 2022 - Springer
Cryopreservation has important application in assisted reproductive technology (ART). The
vitrification technique has been widely used in the cryopreservation of oocytes and embryos …

In-utero stress and mode of conception: impact on regulation of imprinted genes, fetal development and future health

M Argyraki, P Damdimopoulou… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Genomic imprinting is an epigenetic gene regulatory mechanism; disruption
of this process during early embryonic development can have major consequences on both …

[HTML][HTML] DNA methylation, environmental exposures and early embryo development

M Breton-Larrivée, E Elder, S McGraw - Animal reproduction, 2019 - SciELO Brasil
The first crucial step in the developmental program occurs during pre-implantation, the time
after the oocyte has been fertilized and before the embryo implants in the uterus. This period …

[HTML][HTML] Long-Term Effects of ART on the Health of the Offspring

H Ahmadi, L Aghebati-Maleki, S Rashidiani… - International journal of …, 2023 - mdpi.com
Assisted reproductive technologies (ART) significantly increase the chance of successful
pregnancy and live birth in infertile couples. The different procedures for ART, including in …

Should we still perform fresh embryo transfers in ART?

C Blockeel, A Campbell, G Coticchio, J Esler… - Human …, 2019 - academic.oup.com
An increasing number of researchers have alluded to the potential benefit of deferring the
transfer of embryos produced during assisted reproductive technologies (ARTs) away from …

[HTML][HTML] Oocyte and embryo manipulation and epigenetics

E Osman, J Franasiak, R Scott - Seminars in reproductive …, 2018 - thieme-connect.com
Regulation of the epigenome is a mechanism by which the environment influences gene
expression and consequently the health of the individual. The advent and refinement of …

Epigenetic regulation and risk factors during the development of human gametes and early embryos

Y Wang, Q Liu, F Tang, L Yan… - Annual review of …, 2019 - annualreviews.org
Drastic epigenetic reprogramming occurs during human gametogenesis and early embryo
development. Advances in low-input and single-cell epigenetic techniques have provided …

Changes in DNA methylation and imprinting disorders in E9. 5 mouse fetuses and placentas derived from vitrified eight‐cell embryos

Y Ma, Y Ma, L Wen, H Lei, S Chen… - Molecular …, 2019 - Wiley Online Library
Vitrification is increasingly used in assisted reproductive technology (ART) laboratories
worldwide, and potential vitrification‐induced risks require further exploration. The effect of …

Effect of embryo vitrification on the expression of brain tissue proteins in mouse offspring

W Zhu, J Zheng, Y Wen, Y Li, C Zhou… - Gynecological …, 2020 - Taylor & Francis
Vitrification is widely used in assisted reproductive technologies. However, the nervous
system of vitrification offspring is of concern, and research on this is lacking. Vitrification-born …

The effect of vitrification on blastocyst mitochondrial DNA dynamics and gene expression profiles

M Pérez-Sánchez, ML Pardiñas, A Díez-Juan… - Journal of Assisted …, 2023 - Springer
Purpose Does vitrification/warming affect the mitochondrial DNA (mtDNA) content and the
gene expression profile of blastocysts? Methods Prospective cohort study in which 89 …