Liver inflammation and fibrosis
Y Koyama, DA Brenner - The Journal of clinical …, 2017 - Am Soc Clin Investig
Chronic liver inflammation leads to fibrosis and cirrhosis, which is the 12th leading cause of
death in the United States. Hepatocyte steatosis is a component of metabolic syndrome and …
death in the United States. Hepatocyte steatosis is a component of metabolic syndrome and …
Immunity, inflammation and cancer: a leading role for adenosine
Cancer is a complex disease that is dictated by both cancer cell-intrinsic and cell-extrinsic
processes. Adenosine is an ancient extracellular signalling molecule that can regulate …
processes. Adenosine is an ancient extracellular signalling molecule that can regulate …
Microencapsulation of active ingredients in functional foods: From research stage to commercial food products
Q Ye, N Georges, C Selomulya - Trends in Food Science & Technology, 2018 - Elsevier
Background Twelves categories of active ingredients have been recognised to enhance
human health. They are to some extent susceptible to certain conditions such as heat, light …
human health. They are to some extent susceptible to certain conditions such as heat, light …
[HTML][HTML] Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
F Cabreiro, C Au, KY Leung, N Vergara-Irigaray… - Cell, 2013 - cell.com
The biguanide drug metformin is widely prescribed to treat type 2 diabetes and metabolic
syndrome, but its mode of action remains uncertain. Metformin also increases lifespan in …
syndrome, but its mode of action remains uncertain. Metformin also increases lifespan in …
Alcoholic liver disease: pathogenesis and new therapeutic targets
B Gao, R Bataller - Gastroenterology, 2011 - Elsevier
Alcoholic liver disease (ALD) is a major cause of chronic liver disease worldwide and can
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …
lead to fibrosis and cirrhosis. The latest surveillance report published by the National …
Role of oxidative stress in the pathogenesis of nonalcoholic steatohepatitis
The worldwide rising prevalence of obesity and insulin resistance is associated with a
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
parallel increase in nonalcoholic fatty liver disease (NAFLD). NAFLD is characterized by …
Rapid reaction, slow dissociation aggregation, and synergetic multicolor emission for imaging the restriction and regulation of biosynthesis of Cys and GSH
Biosynthesis is a necessary process to maintain life. In recent years, research has fully
shown that three kinds of biothiols (Cys, Hcy, GSH) mainly play the role in oxidative stress …
shown that three kinds of biothiols (Cys, Hcy, GSH) mainly play the role in oxidative stress …
S-adenosylmethionine in Liver Health, Injury, and Cancer
SC Lu, JM Mato - Physiological reviews, 2012 - journals.physiology.org
S-adenosylmethionine (AdoMet, also known as SAM and SAMe) is the principal biological
methyl donor synthesized in all mammalian cells but most abundantly in the liver …
methyl donor synthesized in all mammalian cells but most abundantly in the liver …
Nicotinamide N-methyltransferase: more than a vitamin B3 clearance enzyme
P Pissios - Trends in Endocrinology & Metabolism, 2017 - cell.com
Nicotinamide (NAM) N-methyltransferase (NNMT) was originally identified as the enzyme
responsible for the methylation of NAM, one of the forms of vitamin B3. Methylated NAM is …
responsible for the methylation of NAM, one of the forms of vitamin B3. Methylated NAM is …
[HTML][HTML] A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans
Sterol regulatory element-binding proteins (SREBPs) activate genes involved in the
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …
synthesis and trafficking of cholesterol and other lipids and are critical for maintaining lipid …