Abdominal aortic aneurysm: roles of inflammatory cells
Z Yuan, Y Lu, J Wei, J Wu, J Yang, Z Cai - Frontiers in immunology, 2021 - frontiersin.org
Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …
Vascular smooth muscle cells in aortic aneurysm: from genetics to mechanisms
Aortic aneurysm, including thoracic aortic aneurysm and abdominal aortic aneurysm, is the
second most prevalent aortic disease following atherosclerosis, representing the ninth …
second most prevalent aortic disease following atherosclerosis, representing the ninth …
Gut microbiome dysbiosis contributes to abdominal aortic aneurysm by promoting neutrophil extracellular trap formation
Z Tian, Y Zhang, Z Zheng, M Zhang, T Zhang, J Jin… - Cell host & …, 2022 - cell.com
Abdominal aortic aneurysm (AAA) is an insidious and lethal vascular disease that lacks
effective nonsurgical interventions. Gut microbiota dysbiosis plays key roles in many …
effective nonsurgical interventions. Gut microbiota dysbiosis plays key roles in many …
Extracellular matrix, regional heterogeneity of the aorta, and aortic aneurysm
Aortic aneurysm is an asymptomatic disease with dire outcomes if undiagnosed. Aortic
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
aneurysm rupture is a significant cause of death worldwide. To date, surgical repair or …
NLRP3 inflammasome as a key driver of vascular disease
M Takahashi - Cardiovascular research, 2022 - academic.oup.com
Nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3
(NLRP3) is an intracellular innate immune receptor that recognizes a diverse range of …
(NLRP3) is an intracellular innate immune receptor that recognizes a diverse range of …
[HTML][HTML] Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …
Genetic and epigenetic mechanisms underlying vascular smooth muscle cell phenotypic modulation in abdominal aortic aneurysm
R Gurung, AM Choong, CC Woo, R Foo… - International journal of …, 2020 - mdpi.com
Abdominal aortic aneurysm (AAA) refers to the localized dilatation of the infra-renal aorta, in
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
which the diameter exceeds 3.0 cm. Loss of vascular smooth muscle cells, degradation of …
Gut microbiota–derived trimethylamine N-oxide contributes to abdominal aortic aneurysm through inflammatory and apoptotic mechanisms
Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …
The mechanism and therapy of aortic aneurysms
Aortic aneurysm is a chronic aortic disease affected by many factors. Although it is generally
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
asymptomatic, it poses a significant threat to human life due to a high risk of rupture …
Cigarette smoke extract induces ferroptosis in vascular smooth muscle cells
A Sampilvanjil, T Karasawa… - American Journal …, 2020 - journals.physiology.org
Cigarette smoking is a major risk factor for aortic aneurysm and dissection; however, no
causative link between smoking and these aortic disorders has been proven. In the present …
causative link between smoking and these aortic disorders has been proven. In the present …