Molecular therapies and precision medicine for hepatocellular carcinoma
The global burden of hepatocellular carcinoma (HCC) is increasing and might soon surpass
an annual incidence of 1 million cases. Genomic studies have established the landscape of …
an annual incidence of 1 million cases. Genomic studies have established the landscape of …
Advances in molecular classification and precision oncology in hepatocellular carcinoma
S Rebouissou, JC Nault - Journal of hepatology, 2020 - Elsevier
Hepatocellular carcinoma (HCC) arises from hepatocytes through the sequential
accumulation of multiple genomic and epigenomic alterations resulting from Darwinian …
accumulation of multiple genomic and epigenomic alterations resulting from Darwinian …
The role of angiogenesis in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) accounts for about 90% of all primary liver cancers and is
the second leading cause of cancer-related deaths worldwide. The hypervascular nature of …
the second leading cause of cancer-related deaths worldwide. The hypervascular nature of …
Mechanisms of HBV-induced hepatocellular carcinoma
M Levrero, J Zucman-Rossi - Journal of hepatology, 2016 - Elsevier
Hepatitis B virus (HBV) contributes to hepatocellular carcinoma (HCC) development through
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
direct and indirect mechanisms. HBV DNA integration into the host genome occurs at early …
Genetic landscape and biomarkers of hepatocellular carcinoma
Hepatocellular carcinoma (HCC) has emerged as a major cause of cancer-related death. Its
mortality has increased in Western populations, with a minority of patients diagnosed at …
mortality has increased in Western populations, with a minority of patients diagnosed at …
Treatment for liver cancer: From sorafenib to natural products
S Man, C Luo, M Yan, G Zhao, L Ma, W Gao - European journal of …, 2021 - Elsevier
Liver cancer most commonly develops in patients with chronic liver disease, the etiology of
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
which includes viral hepatitis (B and C), alcohol, obesity, dietary carcinogens, and so forth …
Multiomics identifies the link between intratumor steatosis and the exhausted tumor immune microenvironment in hepatocellular carcinoma
H Murai, T Kodama, K Maesaka, S Tange… - Hepatology, 2023 - journals.lww.com
Multiomics identifies the link between intratumor steatosis... : Hepatology Multiomics
identifies the link between intratumor steatosis and the exhausted tumor immune …
identifies the link between intratumor steatosis and the exhausted tumor immune …
Advances in targeted therapies for hepatocellular carcinoma in the genomic era
JM Llovet, A Villanueva, A Lachenmayer… - Nature reviews Clinical …, 2015 - nature.com
Mortality owing to liver cancer has increased in the past 20 years, and the latest estimates
indicate that the global health burden of this disease will continue to grow. Most patients with …
indicate that the global health burden of this disease will continue to grow. Most patients with …
Hepatocellular carcinoma: clinical frontiers and perspectives
Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death and is
currently the main event leading to death in patients with cirrhosis. Evolving information …
currently the main event leading to death in patients with cirrhosis. Evolving information …
Treatment strategies for hepatocellular carcinoma—a multidisciplinary approach
I Lurje, Z Czigany, J Bednarsch, C Roderburg… - International journal of …, 2019 - mdpi.com
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and its
mortality is third among all solid tumors, behind carcinomas of the lung and the colon …
mortality is third among all solid tumors, behind carcinomas of the lung and the colon …