This article reviews the majority of Congenital Anomalies of the Kidney and Urinary Tract
(CAKUT) with emphasis in Pediatric Pathology describing and illustrating lesions as varied …

Autosomal recessive polycystic kidney disease (ARPKD) belongs to a group of congenital
hepatorenal fibrocystic syndromes and is a cause of significant renal and liver-related …

Background and objectives ADPKD is erroneously perceived as a not rare condition, which
is mainly due to the repeated citation of a mistaken interpretation of old epidemiological …

Acute kidney injury is a common clinical condition associated with increased morbidity and
mortality. It is essential to find effective drugs with low side effects in the treatment of acute …

AIM To investigate the therapeutic potential of tesevatinib (TSV), a unique multi-kinase
inhibitor currently in Phase II clinical trials for autosomal dominant polycystic kidney disease …

Macroautophagy/autophagy is an intracellular process involved in the breakdown of
macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 …

ARPKD is a genetically inherited kidney disease that manifests by bilateral enlargement of
cystic kidneys and liver fibrosis. It shows a range of severity, with 30% of individuals dying …

Autosomal recessive polycystic kidney disease (ARPKD) is a rare disorder and one of the
most severe forms of polycystic kidney disease, leading to end-stage renal disease (ESRD) …

Polycystic kidney disease (PKD) is a genetic disorder characterized by fluid-filled cysts in the
kidney and liver that ultimately leads to end-stage renal disease. Currently there is no …

Background Autosomal recessive polycystic kidney disease (ARPKD) is a rare but frequently
severe disorder that is typically characterized by cystic kidneys and congenital hepatic …